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Dirofilariasis

(Dog Heartworm Infection)

By Richard D. Pearson, MD, Professor of Medicine and Pathology, Associate Dean for Student Affairs, University of Virginia School of Medicine

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Dirofilariasis is a filarial nematode infection with Dirofilaria immitis, the dog heartworm, or other Dirofilaria spp, which are transmitted to humans by infected mosquitoes.

Symptomatic human infection is very rare, but larvae may become encapsulated in infarcted lung tissue and produce well-defined pulmonary nodules; rarely, larvae form nodules in the eyes, brain, and testes.

Patients may have chest pain, cough, and occasionally hemoptysis. Many patients remain asymptomatic, and a pulmonary nodule, which may suggest a tumor, is discovered during routine chest x-ray.

Dirofilariasis is diagnosed by histologic examination of a surgical specimen.

No anthelmintic treatment is indicated in humans; infection is self-limited.

* This is the Professional Version. *