Oxyhemoglobin Dissociation Curve
Oxyhemoglobin Dissociation Curve
Arterial oxyhemoglobin saturation is related to PO2. PO2 at 50% saturation (P50) is normally 27 mm Hg.
The dissociation curve is shifted to the right by increased hydrogen ion (H+) concentration, increased red blood cell 2,3-diphosphoglycerate (DPG), increased temperature (T), and increased PCO2.
Decreased levels of H+, DPG, temperature, and PCO2 shift the curve to the left.
Hemoglobin characterized by a rightward shifting of the curve has a decreased affinity for oxygen, and hemoglobin characterized by a leftward shifting of the curve has an increased affinity for oxygen.
In these topics