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Giant Cell Tumor (CT Scan)

This axial CT scan (left) shows a lytic lesion of the sacrum (red arrow) with anterior soft-tissue mass (white arrow). A biopsy showed giant cell tumor of bone. After 4 yr of denosumab treatment, the follow-up CT scan (right) shows progressive ossification of the tumor (green arrow) without an increase in size.

Image courtesy of Michael J. Joyce, MD, and Hakan Ilaslan, MD.