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Cervical Dystonia

(Spasmodic Torticollis)

By Hector A. Gonzalez-Usigli, MD, Professor of Neurology;Movement Disorders Clinic, HE UMAE Centro Médico Nacional de Occidente;Neurology at IMSS

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Cervical dystonia is characterized by involuntary tonic contractions or intermittent spasms of neck muscles. The cause is usually unknown. Diagnosis is clinical. Treatment can include physical therapy, drugs, and selective denervation of neck muscles with surgery or locally injected botulinum toxin.

In cervical dystonia, contraction of the neck muscles causes the neck to turn from its usual position. It is the most common dystonia.

Spasmodic (adult-onset) torticollis is the most common form of cervical dystonia. It is usually idiopathic. A few patients have a family history, and in some of them (eg, those with dystonia-6 [DYT6], dystonia-7 [DYT7], or dystonia-25 [DYT25; associated with the GNAL gene]), a genetic cause has been identified. Some of these patients have other dystonias (eg, of the eyelids, face, jaw, or hand).

Cervical dystonia can be

  • Congenital

  • Secondary to other conditions such as lesions of the brain stem or basal ganglia or use of dopamine-blocking drugs (eg, haloperidol)

Rarely, dystonia has a psychogenic cause. In this type of dystonia, pathophysiology is not well understood; however, changes in brain function have been detected by functional neuroimaging. In many cases, an emotional stressor or an abnormal core of beliefs is identified as a trigger. In such cases, a multidisciplinary team, including a neurologist, psychiatrist, and psychologist, is necessary.

Symptoms and Signs

Cervical dystonia symptoms may begin at any age but usually begin between ages 20 and 60, with a peak between ages 30 and 50.

Symptoms usually begin gradually; rarely, they begin acutely and progress rapidly. Sometimes symptoms begin with a tremor that rotates the neck (in a no-no gesture).

The cardinal symptom is

  • Painful tonic contractions or intermittent spasms of the sternocleidomastoid, trapezius, and other neck muscles, usually unilaterally, that result in an abnormal head position

Unilateral sternocleidomastoid muscle contraction causes the head to rotate to the opposite side. Rotation may involve any plane but almost always has a horizontal component. Besides rotational tilting (torticollis), the head can tilt laterally (laterocollis), forward (anterocollis), or backward (retrocollis, common when dopamine-blocking drugs are the cause).

Patients may discover sensory or tactile tricks that lessen the dystonic posturing or tremor (eg, touching the face on the side contralateral to the deviation). During sleep, muscle spasms disappear.

Spasmodic torticollis ranges from mild to severe. Usually, it progresses slowly for 1 to 5 yr, then plateaus. About 10 to 20% of patients recover spontaneously within 5 yr of onset (usually in milder cases with onset at a younger age). However, it may persist for life and can result in restricted movement and postural deformity.


  • Clinical evaluation

The diagnosis of cervical dystonia is based on characteristic symptoms and signs and exclusion of alternative diagnoses, including the following:

  • Tardive dyskinesia can cause torticollis but can usually be distinguished by a history of chronic antipsychotic use and involuntary movements in muscles outside of the neck.

  • Basal ganglia disorders and occasionally CNS infections can cause movement disorders but usually also involve other muscles; CNS infections are usually acute and cause other symptoms.

  • Neck infections or tumors are usually differentiated by features of the primary process.

  • Antipsychotics and other drugs can cause acute torticollis, but the symptoms usually develop in hours and resolve within days after the drug is stopped.


  • Physical measures

  • Sometimes botulinum toxin or oral drugs

Spasms can sometimes be temporarily inhibited by physical therapy and massage, including sensory biofeedback techniques (eg, slight tactile pressure to the jaw on the same side as head rotation) and any light touch.


Injections of botulinum toxin type A or B into the dystonic muscles can reduce painful spasms for 1 to 4 mo in about 70% of patients, restoring a more neutral position of the head. However, in a few cases, when the toxin is repeatedly injected, it becomes less effective because neutralizing antibodies against the toxin develop.

Oral drugs can usually relieve pain, but they suppress dystonic movements in only about 25 to 33% of patients. These drugs include

  • Anticholinergic drugs, such as trihexyphenidyl 10 to 25 mg po once/day or bid (but adverse effects may limit their use)

  • Benzodiazepines (particularly clonazepam 0.5 mg po bid)

  • Baclofen

  • Carbamazepine

All drugs should be started in low doses (eg, trihexyphenidyl 2 mg po tid). Doses should be increased until symptoms are controlled or intolerable adverse effects (particularly likely in the elderly) develop.


Surgery is controversial. The most successful surgical approach selectively severs nerves to affected neck muscles, permanently weakening or paralyzing them. Results are favorable when the procedure is done at centers with extensive experience.

Key Points

  • Spasmodic torticollis is a common adult-onset cervical dystonia and is usually idiopathic.

  • Diagnosis is clinical and involves exclusion of tardive dyskinesia, basal ganglia disorders, CNS infections, neck infections and tumors, and drugs.

  • Treatment is most often physical measures, botulinum toxin injection, and/or oral drugs.

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