Merck Manual

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Aztreonam

By

Brian J. Werth

, PharmD, University of Washington School of Pharmacy

Medically Reviewed Jun 2022 | Modified Sep 2022
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Topic Resources

Aztreonam is commonly used to treat people who are allergic to some beta-lactam antibiotics and is used in combination with other antibiotics to treat certain antibiotic-resistant bacteria.

Most bacteria have an outer covering (cell wall) that protects them. Like the other beta-lactam antibiotics, aztreonam works by preventing bacteria from forming this cell wall, resulting in death of the bacteria.

Table

Aztreonam

Common Uses

Some Potential Side Effects

Comments

Injection site discomfort and swelling

Diarrhea, nausea, vomiting, or a combination

Rash

Can typically be used in people allergic to other beta-lactam antibiotics, such as penicillins, cephalosporins, and carbapenems, but should be avoided in people with severe allergies to ceftazidime or cefiderocol

Must be given by injection

Use of Aztreonam During Pregnancy and Breastfeeding

Drugs Mentioned In This Article

Generic Name Select Brand Names
Azactam, Cayston
NOTE: This is the Consumer Version. DOCTORS: VIEW PROFESSIONAL VERSION
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