Your small intestine is where food is absorbed.
Malabsorption Overview of Malabsorption Food you eat has to be digested before it can go into your body. Digestion breaks food down into its separate parts: Proteins Fats Carbohydrates Proteins, fats, and carbohydrates are nutrients... read more is when you have trouble absorbing the nutrients in your food. Nutrients are things that provide nutrition to your body. They include protein, carbohydrates, fats, vitamins, and minerals.
What is Whipple disease?
Whipple disease is a rare infection that damages the lining of your small intestine. You have trouble breaking down (digesting) food and absorbing nutrients.

Whipple disease may affect other organs too, such as your heart, lungs, brain, joints, and eyes.
Symptoms can include diarrhea, swollen and painful joints, weight loss, and belly pain
Antibiotics can treat the infection, but the disease can come back
Without treatment, Whipple disease can be deadly
What are the symptoms of Whipple disease?
The main symptoms of Whipple disease are:
Swollen, painful joints
Diarrhea (frequent, loose, or watery stool)
Belly pain
Weight loss
Other symptoms include:
Fever
Not feeling hungry
Anemia Overview of Anemia Anemia is not having enough red blood cells or hemoglobin. Red blood cells carry oxygen from your lungs to all of your other organs. Hemoglobin is the substance inside your red blood cells that... read more (low red blood cell count), which may make you feel weak and tired
Cough
Swollen lymph nodes
If the infection spreads to your brain—confusion or memory loss
How can doctors tell if I have Whipple disease?
Doctors diagnose Whipple disease by finding the bacteria that causes the disease in a biopsy sample taken from your small intestine. With a biopsy, doctors take a small sample of tissue using instruments on the end of an endoscope (a flexible viewing tube) and then look at the sample under a microscope.
How do doctors treat Whipple disease?
Doctors treat Whipple disease with antibiotics for at least a year. The disease can sometimes come back after treatment.
If untreated, Whipple disease gets worse and can be deadly.