Health issues at the destination are especially important to prevent and avoid in international settings. Certain infections are common when traveling to certain areas, and many people are most concerned about infection when considering a trip overseas. However, motor vehicle crashes and heart disease are the most common causes of death among international travelers. Heart disease is the most common cause of death among nontravelers as well, suggesting that attention to health before leaving home is the best way to prevent illness while away.
Injuries and Death While Traveling
Injuries caused by motor vehicle crashes are the most frequent cause of death among younger and middle-aged travelers. Another common cause of death while traveling is drowning. Common-sense measures can be taken to prevent many such injuries. For example, people uncomfortable with unfamiliar traffic patterns (such as driving on the left side of the road in England versus the right side in the United States) can take public transportation or hire drivers familiar with local roads and traffic laws. Travelers should avoid overcrowded taxis, ferries, or other transports and avoid nighttime driving and swimming in poorly lit areas. People should wear seat belts even as passengers and should use a helmet when bicycling. Travelers should avoid motorcycles and mopeds and avoid riding on bus roofs or in open truck beds. Also, alcohol should never be consumed before driving or swimming, even where laws do not formally prohibit such actions or where laws that do exist are not enforced. People should also avoid beaches with turbulent waves, particularly when lifeguards are not present.
Many cities are unsafe after dark, and some are unsafe even during the day. A traveler should avoid walking alone on poorly lit or deserted streets in such cities, especially in countries where the traveler is obviously a stranger.
Fair-skinned travelers are more vulnerable to sunburn at tropical latitudes and at high altitude. Use of high-SPF (sun protection factor of 30 or higher) sunscreen is advisable. When both sunscreen and insect repellent are used, sunscreen should be applied first, then, after at least fifteen minutes, insect repellent.
Did You Know...
Traveler’s diarrhea Traveler’s Diarrhea Traveler’s diarrhea is an infection characterized by diarrhea, nausea, and vomiting that commonly occur in travelers to areas of the world with poor water purification. Traveler's diarrhea can... read more (turista) is the most common health problem among international travelers. It is caused by bacteria or viruses that have contaminated food or water.
The risk of traveler’s diarrhea may be reduced by the following measures:
Drinking and brushing teeth with bottled, filtered, boiled, UV-treated, or chlorinated water
Eating freshly prepared foods only if they have been heated to steaming temperatures
Eating only fruits and vegetables that people peel or shell themselves
Avoiding food from street vendors
Washing hands frequently
Avoiding all foods likely to have been exposed to flies
Taking certain antibiotics can also prevent traveler’s diarrhea. However, such use has a risk of side effects and may increase the chances that bacteria will develop resistance to antibiotics. Thus, doctors recommend preventive antibiotics only for people who have an immune deficiency disorder.
In most cases, traveler’s diarrhea subsides by itself in about 3 to 5 days and requires only the steady intake of fluids to prevent dehydration. Ordinary clear liquids (without caffeine or alcohol) are adequate for most people. Young children and older people may benefit from powdered rehydration mixes or an oral rehydration solution.
People who have moderate to severe symptoms (symptoms severe enough to disrupt activities) should consider taking an antibiotic, especially if they have vomiting, fever, abdominal cramps, or blood in the stool. Azithromycin is appropriate for most countries and is recommended for children and pregnant women. People should contact their doctor for an antibiotic prescription before travel. If people are 6 years of age or older and have no bloody stools, fever, or abdominal pain, they can also be treated with the antidiarrheal drug loperamide (which is available without a prescription).
For older adults and young children, powdered rehydration mixes are available for travel. If these mixes are unavailable, rehydration solutions can be made by adding 6 teaspoons of sugar and 1 half teaspoon of salt to 1 liter of water. However, solutions should be prepared carefully because young children can become seriously ill or die if they drink much of a solution that has been incorrectly mixed (for example, if a rehydration mix has not been fully diluted).
Malaria in Travelers
malaria Malaria Malaria is infection of red blood cells with one of five species of the protozoa Plasmodium. Malaria causes fever, chills, sweating, a general feeling of illness (malaise), and sometimes... read more is common throughout the tropics. Malaria is prevented by avoiding mosquito bites and taking an antimalarial drug.
Mosquito bites are prevented by the following measures:
Wearing long-sleeved shirts and long trousers (especially at dawn and dusk, when mosquitoes are most active)
Sleeping under a mosquito net
Applying the insecticide permethrin to clothing or purchasing clothing that has been impregnated with permethrin
Using insect repellants that contain diethyltoluamide (DEET) or picaridin
Insect repellants can also help prevent other mosquito-borne diseases such as dengue Dengue Dengue is a mosquito-borne viral infection that causes fever, generalized body aches, and, if severe, external and internal bleeding (called dengue hemorrhagic fever). About 50 to 100 million... read more , Zika Zika Virus Infection Zika virus infection is a mosquito-borne viral infection that typically causes no symptoms but can cause fever, rash, joint pain, or infection of the membrane that covers the white of the eye... read more , and yellow fever Yellow Fever Yellow fever is a mosquito-borne viral disease that occurs mainly in the tropics. Yellow fever occurs only in the tropical areas of Central Africa, southern Panama, and South America. Some people... read more .
Even when people take measures to avoid mosquito bites, it is still necessary to take a drug to prevent malaria Medications to prevent malaria Malaria is infection of red blood cells with one of five species of the protozoa Plasmodium. Malaria causes fever, chills, sweating, a general feeling of illness (malaise), and sometimes... read more (such as mefloquine, chloroquine, doxycycline, or atovaquone/proguanil) when traveling to many parts of the world. Information about specific areas is available from the Centers for Disease Control and Prevention (CDC: Malaria and Travelers).
Pregnant women should consider delaying travel to areas where malaria is common because malaria is more likely to be serious and life threatening among pregnant women than among women who are not pregnant, even when preventive drugs are used. Pregnant women who cannot postpone travel must weigh the risks of taking protective drugs, the effects of which on pregnancy are not well known, against the risks of traveling without protection.
Although the new RTS,S/AS01 (RTS,S) malaria vaccine is recommended for children living in regions with moderate to high Plasmodium falciparum malaria transmission, this vaccine is not recommended for travelers to those regions.
Sexually Transmitted Infections
Sexually transmitted infections, including human immunodeficiency virus (HIV) infection Human Immunodeficiency Virus (HIV) Infection Human immunodeficiency virus (HIV) infection is a viral infection that progressively destroys certain white blood cells and is treated with antiretroviral medications. If untreated, it can cause... read more , gonorrhea Gonorrhea Gonorrhea is a sexually transmitted infection caused by the bacteria Neisseria gonorrhoeae, which infect the lining of the urethra, cervix, rectum, or throat, or the membranes that cover... read more , syphilis Syphilis Syphilis is a sexually transmitted infection caused by the bacteria Treponema pallidum. It can occur in three stages of symptoms, separated by periods of apparent good health. Syphilis... read more , trichomoniasis Trichomoniasis Trichomoniasis is a sexually transmitted infection of the vagina or urethra that is caused by the protozoa Trichomonas vaginalis and that causes vaginal irritation and discharge and sometimes... read more , and hepatitis B Overview of Acute Viral Hepatitis Acute viral hepatitis is inflammation of the liver, generally meaning inflammation caused by infection with one of the five hepatitis viruses. In most people, the inflammation begins suddenly... read more , are more common in low- and middle-income countries. All can be prevented through abstinence or with correct, consistent use of a latex condom (see Prevention of Sexually Transmitted Infections Prevention Sexually transmitted infection (STI) refers to an infection that is passed through blood, semen, vaginal fluids, or other body fluids during oral, anal, or genital sex with an infected partner... read more ). Because HIV and hepatitis B also are transmitted through blood and needles, an international traveler should not accept a blood transfusion without assurance that the blood has been tested for infection. Also, injections should be accepted only through one-time-only disposable needles.
COVID-19 COVID-19 COVID-19 is an acute respiratory illness that can be severe and is caused by the coronavirus named SARS-CoV-2. Symptoms of COVID-19 vary significantly. Two types of tests can be used to diagnose... read more is an acute respiratory illness that can be severe and is caused by the coronavirus named SARS-CoV2. The COVID-19 pandemic necessitated limitation of travel to and from various countries. Entry requirements (for example, testing, vaccination, quarantine) change frequently, and travelers should check the websites of their nation's health agency (for example, in the United States, the Centers for Disease Control and Prevention) as well as those of the destination countries for current recommendations.
Dengue Dengue Dengue is a mosquito-borne viral infection that causes fever, generalized body aches, and, if severe, external and internal bleeding (called dengue hemorrhagic fever). About 50 to 100 million... read more is a mosquito-borne viral infection that causes fever, generalized body aches, and, if severe, external and internal bleeding (called dengue hemorrhagic fever). Dengue is common in the tropics and subtropics worldwide. It is most common in Southeast Asia but has become more common in Central and South America and other countries. It has occurred in the Caribbean (including Puerto Rico and the U.S. Virgin Islands), in Oceania, and in the Indian subcontinent.
A vaccine is available in Mexico, Brazil, Thailand, and some other countries (not in the United States), but use is restricted to people who have previously had dengue.
Mosquito bite prevention is important for people traveling to areas where dengue is common.
Wear clothing that covers as much of the body as possible
Wear clothing to which the insecticide permethrin has been applied and sleep under a permethrin-treated mosquito net if sleeping quarters are not air conditioned
Use insect repellants, such as DEET (diethyltoluamide) or picaridin
Avoid exposure to mosquitoes and ticks as much as possible
These measures also offer protection from other insect-transmitted diseases including Zika Zika Virus Infection Zika virus infection is a mosquito-borne viral infection that typically causes no symptoms but can cause fever, rash, joint pain, or infection of the membrane that covers the white of the eye... read more and chikungunya Arboviruses Arbovirus, arenavirus, and filovirus are viruses that are spread from animals to people and, with some viruses, from people to people. The animal involved depends on the type of virus. Many... read more . (See CDC: Prevent Mosquito Bites.)
Influenza Influenza (Flu) Influenza (flu) is a viral infection of the lungs and airways with one of the influenza viruses. It causes a fever, runny nose, sore throat, cough, headache, muscle aches (myalgias), and a general... read more (flu) is a viral infection of the lungs and airways with one of the influenza viruses. It is common in international travelers. An annual influenza vaccines Influenza Vaccine The influenza virus vaccine helps protect against influenza. Two types of influenza virus, type A and type B, regularly cause seasonal epidemics of influenza in the United States. There are... read more is the best way to prevent influenza.
Schistosomiasis Schistosomiasis Schistosomiasis is infection caused by certain flatworms (flukes), called schistosomes. People acquire schistosomiasis by swimming or bathing in fresh water that is contaminated with the flukes... read more is a common and potentially serious infection caused by a parasite that lives in freshwater in Africa, Southeast Asia, China, and eastern South America. The risk of schistosomiasis can be reduced by avoiding freshwater activities in areas where schistosomiasis is common. Asymptomatic travelers with freshwater exposure in regions where schistosomiasis is common should be screened for the parasite after returning from such regions.
Lice and Scabies
Lice Lice Infestation Lice infestation is a parasitic skin infestation caused by tiny wingless insects. Lice spread most frequently through close person-to-person contact. People with lice usually have severe itching... read more and scabies Scabies Infestation Scabies is a parasitic skin infestation caused by mites. Scabies usually spreads from person to person through physical contact. People with scabies have severe itching, even though there are... read more are common in crowded accommodations, underdeveloped areas, and places where hygiene measures are poor. They can be treated with permethrin, malathion, or lindane lotions. However, these lotions should not be used preventively.
Zika virus Zika Virus Infection Zika virus infection is a mosquito-borne viral infection that typically causes no symptoms but can cause fever, rash, joint pain, or infection of the membrane that covers the white of the eye... read more infection causes few or only mild symptoms in adults. However, Zika infection during pregnancy can cause serious birth defects in the baby.
Zika virus infection is spread by mosquitoes and also by sexual contact and transfusion of blood from an infected person. The disease has spread widely through South and Central America, the Caribbean, South Asia, Southeast Asia, and Pacific Islands. The Centers for Disease Control and Prevention (CDC) recently reported that all of the cases of Zika virus infection in the United States were in travelers returning from affected areas. There were no reports of Zika virus infection spread by local mosquitoes or through sexual contact. The CDC recommends that pregnant women consider postponing travel to areas where Zika virus infection is common (see CDC: Zika Virus: For Pregnant Women and CDC Zika Travel Information).
The following English-language resource may be useful. Please note that THE MANUAL is not responsible for the content of this resource.
Centers for Disease Control and Prevention: Travelers' Health
Drugs Mentioned In This Article
|Generic Name||Select Brand Names|
|Cafcit, NoDoz, Stay Awake, Vivarin|
|Azasite, Zithromax, Zithromax Powder, Zithromax Single-Dose , Zithromax Tri-Pak, Zithromax Z-Pak, Zmax, Zmax Pediatric|
|Anti-Diarrheal, Imodium A-D, Imodium A-D EZ Chews , K-Pek II|
|Acticin, Elimite, Nix Lice Killing Creme Rinse|
|Acticlate, Adoxa, Adoxa Pak, Avidoxy, Doryx, Doxal, Doxy 100, LYMEPAK, Mondoxyne NL, Monodox, Morgidox 1x, Morgidox 2x , Okebo, Oracea, Oraxyl, Periostat, TARGADOX, Vibramycin, Vibra-Tabs|
|Malarone, Malarone Pediatric|
|G B H , GBH, Lindane|