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Intraamniotic Infection



Antonette T. Dulay

, MD, Main Line Health System

Reviewed/Revised Oct 2022

Intraamniotic infection is infection of the tissues around the fetus, such as the fluid that surrounds the fetus (amniotic fluid), the placenta, the membranes around the fetus, or a combination.

  • Intraamniotic infection increases the risk of problems in the woman and in the fetus.

  • Women usually have a fever and often have pelvic pain and a vaginal discharge.

  • Usually, doctors can diagnose the infection by doing a physical examination, but sometimes amniotic fluid must be analyzed.

  • Women are given antibiotics and drugs to lower body temperature, and delivery is scheduled as soon as possible.

Pregnancy complications, such as intraamniotic infection, are problems that occur only during pregnancy. They may affect the woman, the fetus, or both and may occur at different times during the pregnancy. However, most pregnancy complications can be effectively treated.

Risk factors for intraamniotic infection

Intraamniotic infection typically develops because bacteria from the vagina enter the uterus and infect the tissues around the fetus. Normally, mucus in the cervix, the membranes around the fetus, and the placenta prevent bacteria from causing infection. However, certain conditions can make it easier for bacteria to breach these defenses.

Intraamniotic infection is also more likely if

Rarely, infection occurs when internal fetal monitoring Fetal monitoring Labor is a series of rhythmic, progressive contractions of the uterus that gradually move the fetus through the lower part of the uterus (cervix) and birth canal (vagina) to the outside world... read more is done. For this procedure, doctors monitor the fetus by inserting an electrode (a small round sensor attached to a wire) through the woman’s vagina and attached to the fetus’s scalp.

Complications of intraamniotic infection

Intraamniotic infection can increase the risk of the following problems in the fetus or newborn:

Intraamniotic infection can cause as well as result from preterm delivery or preterm premature rupture of the membranes.

Intraamniotic infection can increase the risk of the following problems in the woman:

Symptoms of Intraamniotic Infection

Intraamniotic infection usually causes fever and often causes abdominal pain and a discharge that can be foul-smelling. The heart rate of the fetus and the woman may be rapid. However, some women do not have typical symptoms.

Diagnosis of Intraamniotic Infection

  • A doctor's evaluation

  • A complete blood count

  • Sometimes amniocentesis

Doctors do a physical examination and a complete blood count (which includes a white blood cell count).

An intraamniotic infection is suspected when women have a fever and at least one other typical symptom, such as a fast heart rate in the fetus or a foul-smelling discharge or an abnormally high white blood cell count in the woman. If the diagnosis is still unclear, doctors can remove a sample of the amniotic fluid and analyze it (amniocentesis Amniocentesis Prenatal diagnostic testing involves testing the fetus before birth (prenatally) to determine whether the fetus has certain abnormalities, including certain hereditary or spontaneous genetic... read more ).

If preterm labor or premature rupture of membranes occurs, doctors consider the possibility of infection even if women do not have typical symptoms.

Prevention of Intraamniotic Infection

If women have preterm premature rupture of the membranes, doctors do pelvic examinations only if necessary.

Doctors usually also give these women antibiotics intravenously and by mouth to help the pregnancy last longer and reduce the risk of problems in the fetus.

Treatment of Intraamniotic Infection

  • Antibiotics

  • Drugs to lower body temperature

  • Delivery

Women with an intraamniotic infection are given antibiotics intravenously. They are also given drugs (preferably acetaminophen before delivery) to lower body temperature.

Delivery should not be delayed once the diagnosis is made.

Drugs Mentioned In This Article

Generic Name Select Brand Names
7T Gummy ES, Acephen, Aceta, Actamin, Adult Pain Relief, Anacin Aspirin Free, Apra, Children's Acetaminophen, Children's Pain & Fever , Comtrex Sore Throat Relief, ED-APAP, ElixSure Fever/Pain, Feverall, Genapap, Genebs, Goody's Back & Body Pain, Infantaire, Infants' Acetaminophen, LIQUID PAIN RELIEF, Little Fevers, Little Remedies Infant Fever + Pain Reliever, Mapap, Mapap Arthritis Pain, Mapap Infants, Mapap Junior, M-PAP, Nortemp, Ofirmev, Pain & Fever , Pain and Fever , PAIN RELIEF , PAIN RELIEF Extra Strength, Panadol, PediaCare Children's Fever Reducer/Pain Reliever, PediaCare Children's Smooth Metls Fever Reducer/Pain Reliever, PediaCare Infant's Fever Reducer/Pain Reliever, Pediaphen, PHARBETOL, Plus PHARMA, Q-Pap, Q-Pap Extra Strength, Silapap, Triaminic Fever Reducer and Pain Reliever, Triaminic Infant Fever Reducer and Pain Reliever, Tylenol, Tylenol 8 Hour, Tylenol 8 Hour Arthritis Pain, Tylenol 8 Hour Muscle Aches & Pain, Tylenol Arthritis Pain, Tylenol Children's, Tylenol Children's Pain+Fever, Tylenol CrushableTablet, Tylenol Extra Strength, Tylenol Infants', Tylenol Infants Pain + Fever, Tylenol Junior Strength, Tylenol Pain + Fever, Tylenol Regular Strength, Tylenol Sore Throat, XS No Aspirin, XS Pain Reliever
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