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How To Do an Inferior Alveolar Nerve Block


Peter J. Heath

, DDS, MD, American Board of Oral and Maxillofacial Surgery

Reviewed/Revised Jul 2022 | Modified Sep 2022
Topic Resources

An inferior alveolar nerve block, the most common dental nerve block, anesthetizes the ipsilateral hemi-mandible (including teeth and bone), as well as the lateral (buccal) mucosa over the lower incisors, canine, and first premolar, and, cutaneously, the ipsilateral lower lip and chin.

The lingual nerve lies nearby and is usually blocked incidentally, anesthetizing the ipsilateral floor of the mouth, medial (lingual) gingiva, and anterior two thirds of the tongue.

A buccal block (of the long buccal nerve) is often done as part of the inferior alveolar nerve block procedure, if anesthetization of the lateral (buccal) gingiva and mucosa of the lower molars and second premolar is needed.



Absolute contraindications

Relative contraindications

  • Infection in the path of needle insertion: Use procedural sedation or other anesthesia.

  • Coagulopathy*: When feasible, correct prior to procedure.

  • Pregnancy: Avoid treatment in the 1st trimester if it can wait.


  • Allergic reaction to the anesthetic

  • Toxicity due to anesthetic overdose (eg, seizure, cardiac arrhythmias)

  • Intravascular injection of anesthetic/epinephrine

  • Hematoma

  • Neuropathy

  • Spread of infection, by passing the needle through an infected area

  • Anesthetization of branches of facial nerve (cranial nerve VII) due to excessively posterior needle placement

  • Failure to anesthetize

  • Needle breakage and loss of needle within soft tissues

Most complications result from inaccurate needle placement.


  • Dental chair, straight chair with head support, or stretcher

  • Light source for intraoral illumination

  • Nonsterile gloves

  • Mask and safety glasses, or a face shield

  • Gauze pads

  • Cotton-tipped applicators

  • Dental mirror or tongue blade

  • Suction

Equipment to do local anesthesia:

  • Topical anesthetic ointment* (eg, lidocaine 5%, benzocaine 20%)

  • Injectable local anesthetic such as lidocaine 2% with epinephrine† 1:100,000, or for longer duration anesthesia, bupivacaine 0.5% with epinephrine† 1:200,000

  • Dental aspirating syringe (with narrow barrel and custom injectable anesthetic cartridges) or other narrow barrel syringe (eg, 3 mL) with locking hub

  • 25- or 27-gauge needle: 3-cm long for nerve blocks

* CAUTION: All topical anesthetic preparations are absorbed from mucosal surfaces, and toxicity may result when dose limits are exceeded. Ointments are easier to control than less-concentrated topical liquids and gels. Excess benzocaine rarely may cause methemoglobinemia.

† Maximum dose of local anesthetics: Lidocaine without epinephrine, 5 mg/kg; lidocaine with epinephrine, 7 mg/kg; bupivacaine, 1.5 mg/kg. NOTE: A 1% solution (of any substance) represents 10 mg/mL (1 gm/100 mL). Epinephrine causes vasoconstriction, which prolongs the anesthetic effect; this is useful in well-vascularized tissues such as the oral mucosa. Patients with cardiac disease should receive only limited amounts of epinephrine (maximum 3.5 mL of solution containing 1:100,000 epinephrine); alternatively, use local anesthetic without epinephrine.

Additional Considerations

  • Document any preexisting nerve deficit before doing a nerve block.

  • Sedation may be needed for patients unable to cooperate with the procedure.

  • Nerve block may fail if the anesthetic is not placed sufficiently close to the nerve.

  • Use a new needle with each attempt (the previous needle may have become blocked with tissue or blood, which would thus obscure inadvertent intravascular placement).

  • Stop the nerve block procedure and use a different method of anesthesia if you are unsure where the needle is or if the patient is uncooperative.

Relevant Anatomy

  • The inferior alveolar nerve is a branch of the mandibular nerve, which is the 3rd branch of the trigeminal nerve.

  • The inferior alveolar nerve travels inferiorly and anteriorly on the medial side of the mandibular ramus. The nerve, accompanied by the inferior alveolar artery and vein, enters the mandibular foramen near the midpoint of the ramus. From this point, the nerve runs within and innervates the body of the mandible; a terminal branch, the mental nerve, reemerges through the mental foramen in the premolar region to innervate the lower lip and chin, as well as the lateral mucosa/gingiva overlying the lower incisor teeth, canine, and first premolar. After this branching, the inferior alveolar nerve continues anteriorly as the incisive nerve, to innervate the remaining teeth and bone anterior to the mental foramen up to the midline.

  • The lingula is the bony protuberance at the anterior margin of the mandibular foramen.

  • The coronoid notch (retromolar fossa) is the concavity of the anterior edge of the ramus, located posterior to the molars.

  • The pterygomandibular triangle is a fatty space bordered laterally by the coronoid notch, and medially by the pterygomandibular raphe.

  • The pterygomandibular raphe is a thin vertical band (a visible tendinous line where the buccinator and the superior pharyngeal constrictor muscles join) that borders the pterygomandibular triangle medially.

  • The needle is inserted posterolaterally into the pterygomandibular triangle, parallel to and about 1 cm above the mandibular occlusal plane. The needle will encounter resistance as it passes through muscle and connective tissue.

  • The anesthetic is ideally placed superiorly and posteriorly adjacent to the lingula (ie, just above the mandibular foramen).

  • The lingual nerve (also a branch of the mandibular nerve) runs near the injection zone and is typically anesthetized incidentally to the inferior alveolar nerve block.


  • Position the patient slightly inclined (semi-recumbent sitting position), with the occiput supported and the mouth opened wide, such that the injection site (medial side of the ramus) is accessible.

  • Right-handed operators should stand on the patient's right and left-handed operators on the patient's left.

Step-by-Step Description of Procedure


  • Wear nonsterile gloves and a mask and safety glasses, or a face shield.

  • Use gauze to thoroughly dry the pterygomandibular triangle. Use suction as needed to keep the area dry.

  • Apply a small amount of topical anesthetic with cotton-tipped applicators and wait 2 to 3 minutes for the anesthesia to occur.

Inject the local anesthetic

  • Instruct the patient to open the mouth comfortably wide.

  • Place the tip of your thumb or forefinger into the coronoid notch, to help visualize the vertical height at which the needle will enter, and retract the cheek to expose the pterygomandibular triangle.

  • Place and maintain the barrel of the syringe over the contralateral lower 1st and 2nd premolars.

  • Keep the needle parallel to—and about 1 cm above—the mandibular occlusal plane, at the vertical plane of the coronoid notch.

  • To establish the correct angle of approach and entry point, rest the side of the needle tip against the lateral edge of the pterygomandibular raphe, such that the tip now aims into the pterygomandibular triangle, with the bevel facing the ramus. Maintain this angle of insertion as you advance the needle.

  • Advance the needle tip slightly into the mucosa. Aspirate, to rule out intravascular placement, and inject a few drops of anesthetic to relieve the pain of the needle insertion itself. Repeat these small injections after incremental advancements of slightly < 1 cm.

    If the patient experiences a sudden, sharp paresthesia, reassure the patient that means the needle is in the right spot. Slightly withdrawing and then redirecting the needle may relieve this sensation, but maintain direction toward the medial ramus and mandibular foramen.

  • Advance the needle until it is stopped by the ramus (typically after about 2 to 2.5 cm of insertion) and withdraw needle 1 mm away from bone.

    If the needle does not hit mandibular bone, it may be too far posterior (eg, into the parotid). Withdraw the needle and redirect it (more anteriorly/laterally).

  • Once contact with the ramus is made, withdraw the needle 1 mm away from the bone.

  • Aspirate, to rule out intravascular placement.

  • If aspiration reveals intravascular placement, withdraw the needle 2 to 3 mm, then re-aspirate prior to injection.

  • Slowly inject about 2 to 4 mL anesthetic, but leave about 0.5 mL in the syringe to block the buccal nerve.

Block the buccal nerve

  • Withdraw the syringe and reinsert it just anterior and lateral to the anterior edge of the ramus at the level of the occlusal surface of the most posterior molar. Advance the needle posteriorly about 3 to 5 mm. Aspirate, to rule out intravascular placement, and inject about 0.25 mL of anesthetic.

  • Massage the injection sites to hasten the onset of anesthesia.

How To Do an Inferior Alveolar Nerve Block


  • Have the patient rest, with mouth relaxed, while awaiting onset of anesthesia (5 to 10 minutes).

Warnings and Common Errors

Tricks and Tips

  • Distraction techniques (eg, talking to the patient or having the patient hold someone else's hand) may help to reduce patient anxiety.

  • Inject the local anesthetic solution slowly (30 to 60 seconds) to reduce the pain of injection.

Drugs Mentioned In This Article

Drug Name Select Trade
Adrenaclick, Adrenalin, Auvi-Q, Epifrin, EpiPen, Epipen Jr , Primatene Mist, SYMJEPI, Twinject
7T Lido, Akten , ALOCANE, ANASTIA, AneCream, Anestacon, Aspercreme with Lidocaine, AsperFlex, Astero , BenGay, Blue Tube, Blue-Emu, CidalEaze, DermacinRx Lidocan III, DermacinRx Lidogel, DermacinRx Lidorex, DERMALID, Dologesic, Ela-Max, GEN7T, Glydo, Gold Bond, LidaFlex, LidaMantle, Lido King Maximum Strength, Lidocan, Lidocare, Lidoderm, LidoDose, LidoDose Pediatric, Lidofore, LidoHeal-90, LIDO-K , LidoLite, Lidomar , Lidomark, LidoPure, LidoReal-30, LidoRx, Lidosense 4 , Lidosense 5, Lidosol, Lidosol-50, LIDO-SORB, Lidotral, Lidovix L, LIDOZION, Lidozo, LMX 4, LMX 4 with Tegaderm, LMX 5, LTA, Lubricaine For Her, Lydexa, Moxicaine, Numbonex, ReadySharp Lidocaine, RectaSmoothe, RectiCare, Salonpas Lidocaine, Senatec, Solarcaine, SUN BURNT PLUS, Tranzarel, Xyliderm, Xylocaine, Xylocaine Dental, Xylocaine in Dextrose, Xylocaine MPF, Xylocaine Topical, Xylocaine Topical Jelly, Xylocaine Topical Solution, Xylocaine Viscous, Zilactin-L, Zingo, Zionodi, ZTlido
Advocate Pain Relief Stick, Americaine, Anbesol, Anbesol Baby , Anbesol Jr , Banadyne-3, Benzodent, Benz-O-Sthetic, Boil-Ease, Cepacol Sensations, Chloraseptic, Comfort Caine , Dry Socket Remedy, Freez Eez, HURRICAINE, HURRICAINE ONE, Little Remedies for Teethers, Monistat Care, Orabase, OraCoat CankerMelts, Orajel, Orajel Baby, Orajel Denture Plus, Orajel Maximum Strength, Orajel P.M., Orajel Protective, Orajel Severe Pain, Orajel Swabs, Orajel Ultra, Oral Pain Relief , Oticaine , Otocain, Outgro, Pinnacaine, Pro-Caine, RE Benzotic, Topex, Topicale Xtra, Zilactin-B
Marcaine, Marcaine Spinal, POSIMIR, Sensorcaine, Sensorcaine MPF , Xaracoll
NOTE: This is the Professional Version. CONSUMERS: View Consumer Version
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