Merck Manual

Please confirm that you are a health care professional

honeypot link

HACEK Infections

By

Larry M. Bush

, MD, FACP, Charles E. Schmidt College of Medicine, Florida Atlantic University;


Maria T. Vazquez-Pertejo

, MD, FACP, Wellington Regional Medical Center

Last full review/revision Feb 2020| Content last modified Feb 2020
Click here for Patient Education

The HACEK group includes weakly virulent, gram-negative organisms that primarily cause endocarditis. Treatment is with antibiotics.

The HACEK group of nonmotile, gram-negative bacilli or coccobacilli contains a number of minimally pathogenic, slow-growing, fastidious genera. Their primary pathology is endocarditis Infective Endocarditis Infective endocarditis is infection of the endocardium, usually with bacteria (commonly, streptococci or staphylococci) or fungi. It may cause fever, heart murmurs, petechiae, anemia, embolic... read more Infective Endocarditis in susceptible people; about 5% of endocarditis cases are due to this group, making them the most common causes of gram-negative bacilli endocarditis. The group consists of

Antibiotic sensitivities differ among species, so treatment should be directed by susceptibility testing. However, increasing beta-lactam resistance has made ceftriaxone and ampicillin/sulbactam the current antibiotics of choice.

Click here for Patient Education
NOTE: This is the Professional Version. CONSUMERS: Click here for the Consumer Version
Professionals also read
Test your knowledge
COVID-19
COVID-19 is an acute, sometimes severe, respiratory illness caused by a novel coronavirus SARS-CoV-2. If a person has been exposed to COVID-19 via a contagious person, quarantining may be necessary based on specific criteria. According to current CDC guidelines, which of the following individuals should quarantine?
Download the Manuals App iOS ANDROID
Download the Manuals App iOS ANDROID
Download the Manuals App iOS ANDROID
Download the Manuals App iOS ANDROID
Download the Manuals App iOS ANDROID
Download the Manuals App iOS ANDROID

Also of Interest

Download the Manuals App iOS ANDROID
Download the Manuals App iOS ANDROID
Download the Manuals App iOS ANDROID
TOP