Merck Manual

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Oxazolidinones: Linezolid and Tedizolid

By

Brian J. Werth

, PharmD, University of Washington School of Pharmacy

Reviewed/Revised Jun 2022 | Modified Sep 2022
VIEW PROFESSIONAL VERSION
Topic Resources

Oxazolidinones include the following:

  • Linezolid

  • Tedizolid

Oxazolidinones work by preventing bacteria from producing proteins they need to grow and multiply.

Table

Oxazolidinones

Drug

Common Uses

Some Potential Side Effects

Linezolid

Nausea and diarrhea

Headache

Anemia and low white blood cell and platelet counts

Numbness and tingling in the hands and feet (peripheral neuropathy)

Visual disturbances

Serotonin syndrome (confusion, agitation, tremors, or coma) in some people who have growths that sometimes produce excessive amounts of hormone-like substances (such as serotonin) or take selective serotonin-reuptake inhibitors Selective serotonin reuptake inhibitors (SSRIs) Several types of medications can be used to treat depression: Selective serotonin reuptake inhibitors (SSRIs) Norepinephrine-dopamine reuptake inhibitors, serotonin modulators, and serotonin-norepinephrine... read more , monamine oxidase inhibitors, or some other drugs that affect serotonin levels

Tedizolid

Gastrointestinal upset

Headache

Anemia and a low white blood cell count

Use of Linezolid and Tedizolid During Pregnancy and Breastfeeding

Drugs Mentioned In This Article

Generic Name Select Brand Names
Zyvox, Zyvox Powder, Zyvox Solution
SIVEXTRO
NOTE: This is the Consumer Version. DOCTORS: VIEW PROFESSIONAL VERSION
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