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Quinupristin and Dalfopristin

By

Brian J. Werth

, PharmD, University of Washington School of Pharmacy

Last full review/revision Jun 2022| Content last modified Sep 2022
CLICK HERE FOR THE PROFESSIONAL VERSION
Topic Resources

Quinupristin and dalfopristin belong to a class of antibiotics Overview of Antibiotics Antibiotics are drugs used to treat bacterial infections. They are not effective against viral infections and most other infections. Antibiotics either kill bacteria or stop them from reproducing... read more called streptogramins. These drugs are given together as a combination (quinupristin/dalfopristin). They are used to treat serious infections (especially skin infections), including those caused by bacteria resistant to other antibiotics.

Quinupristin/dalfopristin works by preventing bacteria from producing proteins they need to grow and multiply.

Quinupristin/dalfopristin is given intravenously, usually through a tube (catheter) inserted into a large central vein, such as one in the neck. This is called a central catheter. Quinupristin/dalfopristin can also be given intravenously into a vein in the upper arm and threaded to a large central vein. This is called a peripherally inserted central catheter, or a PICC.

Table

Quinupristin/Dalfopristin

Common Uses

Some Potential Side Effects

Serious infections caused by gram-positive bacteria Staining and Examination Using a Microscope (such as Staphylococcus and Streptococcus species) that are resistant to other antibiotics

Aching muscles and joints

Pain and inflammation at the site where the catheter was inserted, especially if inserted in a vein in an arm or leg

* Bilirubin is a waste product that is formed during the normal breakdown of red blood cells. Bilirubin is processed and then excreted out of the liver.

Use of Quinupristin/Dalfopristin During Pregnancy and Breastfeeding

Drugs Mentioned In This Article

Generic Name Select Brand Names
SYNERCID
NOTE: This is the Consumer Version. DOCTORS: CLICK HERE FOR THE PROFESSIONAL VERSION
CLICK HERE FOR THE PROFESSIONAL VERSION
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