(See also Introduction to Disorders of Kidney Tubules Introduction to Disorders of Kidney Tubules The kidneys filter and cleanse the blood. They also maintain the body’s balance of water, electrolytes (such as sodium, potassium, bicarbonate, and chloride), and nutrients in the blood. The... read more .)
Normally, the body excretes glucose in the urine only when glucose levels in the blood are very high (such as in uncontrolled diabetes mellitus Diabetes Mellitus (DM) Diabetes mellitus is a disorder in which the body does not produce enough or respond normally to insulin, causing blood sugar (glucose) levels to be abnormally high. Symptoms of diabetes may... read more ). In most healthy people, glucose that is filtered from the blood by the kidneys is completely reabsorbed back into the blood. In people with renal glucosuria, glucose may be excreted in the urine despite normal or low levels of glucose in the blood. This happens because of a defect in the tubular cells of the kidneys Introduction to Disorders of Kidney Tubules The kidneys filter and cleanse the blood. They also maintain the body’s balance of water, electrolytes (such as sodium, potassium, bicarbonate, and chloride), and nutrients in the blood. The... read more that decreases the reabsorption of glucose.
Some forms of renal glucosuria are hereditary, causing glucosuria alone or as part of Fanconi syndrome Fanconi Syndrome Fanconi syndrome is a rare disorder of kidney tubule function that results in excess amounts of glucose, bicarbonate, phosphates (phosphorus salts), uric acid, potassium, and certain amino acids... read more . The acquired form can be caused by certain drugs or diseases that damage the kidney tubules.
Renal glucosuria has no symptoms or serious consequences.
A doctor makes the diagnosis when a routine urine test detects glucose in the urine even though glucose levels in the blood are normal.
No treatment is needed.
The following is an English-language resource that may be useful. Please note that THE MANUAL is not responsible for the content of this resource.
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK): Insight into ongoing research, consumer health information in English and Spanish, a blog, and community health and outreach programs.