Chelation, a biologically based practice, describes a chemical reaction in which certain molecules bind to metal atoms (such as calcium, copper, iron, or lead). Chelating drugs, such as ethylenediaminetetraacetic acid (EDTA), bind with metals so that they can be excreted from the body. Such drugs are commonly used in conventional medicine to treat lead poisoning, iron overdose, and other heavy metal poisonings. (See also Overview of Integrative, Complementary, and Alternative Medicine.)
Practitioners of chelation therapy believe that many disorders are caused by having too much of a metal in the body even when people were not exposed to the metal and blood tests do not show high levels of the metal. Thus, they treat many different disorders with chelating drugs.
Chelation therapy with EDTA has also been suggested as a way to remove calcium and thus treat atherosclerosis and help prevent heart attacks and strokes. However, studies suggest that these benefits of chelation therapy are insignificant or nonexistent.