Gynecologic cancers often involve the uterus, ovaries, cervix, vulva, vagina, fallopian tubes, or the peritoneum. The most common gynecologic cancer in the US is endometrial cancer, followed by ovarian cancer. Cervical cancer is not very common in developed countries because screening with the Papanicolaou (Pap) test and with human papillomavirus (HPV) testing are widely available and effective.
Gestational trophoblastic disease is a gynecologic tumor that may behave aggressively whether malignant or not.
Many gynecologic cancers manifest as pelvic masses.