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Cushing Syndrome

(Cushing's Syndrome)

By

The Manual's Editorial Staff

Last full review/revision Oct 2020| Content last modified Oct 2020
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Glands make and release hormones.

Hormones are chemicals that stimulate other cells or tissues into action. Because hormones are in your blood, they travel throughout your body. They can affect many organs at the same time.

You have two adrenal glands, one above each kidney. The adrenal glands Overview of the Adrenal Glands Glands make and release hormones. Hormones are chemicals that stimulate other cells or tissues into action. Because hormones are in your blood, they travel throughout your body. They can affect... read more release several different hormones that help control your blood pressure, heart rate, balance of water and salt, response to stress, and some male-type sex features.

What is Cushing syndrome?

In Cushing syndrome, you have too much of the adrenal hormone called cortisol.

  • Cushing syndrome is usually caused by your adrenal glands making too much cortisol

  • People with Cushing syndrome often have a very round face, hair loss, depression, and thin skin that bruises easily

  • Treatment for Cushing syndrome depends on what's causing it—you may need surgery or radiation

What causes Cushing syndrome?

Cushing syndrome is usually due to:

  • Your adrenal glands making too much cortisol

  • Taking a corticosteroid medicine such as prednisone for a long time

Your adrenal glands may make too much cortisol if you have:

What is Cushing disease?

Cushing disease is a little different from Cushing syndrome. In Cushing disease, an overactive pituitary gland tells your adrenals glands to make too many hormones.

Cushing disease usually happens when there is a tumor on your pituitary gland. Doctors remove the tumor with surgery or destroy it with radiation.

What are the symptoms of Cushing syndrome?

Symptoms include:

  • Large amounts of belly fat and fat at the top of your back (called a "buffalo hump")

  • Round, swollen face

  • Thin skin that bruises easily and heals slowly

  • Purple streaks that look like stretch marks on your chest and belly

  • Getting tired easily

  • Sometimes, extra face and body hair

  • In women, sometimes hair loss

Children with Cushing syndrome grow slowly and stay short.

Over time, if your Cushing syndrome is untreated, you may have:

How do doctors tell if I have Cushing syndrome?

How do doctors treat Cushing syndrome?

Doctors will:

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Test your knowledge

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Fractures to one or more facial structures can result from a single injury. Jaw fractures may occur to the mandible, or lower jaw, or to the maxilla, bone of the upper jaw. Other structures susceptible to fracture include the eye sockets, nose, and cheek bones. Which of the following facial structures is most likely to fracture if a person falls from a great height or hits the windshield of a car face-first during a motor vehicle accident?
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