Merck Manual

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Symptoms of Nutrient Deficiencies

Symptoms of Nutrient Deficiencies




Bone pain and deformities, greater likelihood of fractures (due to bone thinning or osteoporosis), muscle spasms, tooth discoloration, and greater susceptibility to painful tooth decay

Fatigue and weakness (due to anemia)

Fatigue and weakness (due to anemia)


Muscle spasms

Diarrhea, skin disorders, confusion (pellagra), and sore tongue


Swelling (edema), usually in the legs; dry skin; and hair loss

Night blindness

Vitamin B1

Pins-and-needles sensation, especially in the feet, and heart failure

Vitamin B2

Sore tongue and cracks at the edges of the mouth

Fatigue and weakness (due to anemia), pins-and-needles sensation, and confusion

Weakness and bleeding gums

Bone thinning and bone pain

Tendency to bruise and bleed