Merck Manual

Please confirm that you are not located inside the Russian Federation

honeypot link

Residual Limb Pain

(Phantom Pain; Phantom Sensation)


Jan J. Stokosa

, CP, American Prosthetics Institute, Ltd

Reviewed/Revised Jan 2021 | Modified Sep 2022


Causes of residual-limb pain include

A person with residual-limb pain should first check for signs of infection Skin infection Skin that comes in contact with the socket of the prosthesis must be cared for and carefully checked to prevent skin breakdown and skin infection. Skin breakdown is when the skin is damaged... read more and skin breakdown Skin breakdown Skin that comes in contact with the socket of the prosthesis must be cared for and carefully checked to prevent skin breakdown and skin infection. Skin breakdown is when the skin is damaged... read more . If infection looks likely, the doctor should be consulted. Even if there is no obvious signs of infection, the doctor should be consulted if pain is severe and sudden or if there is fever; these symptoms may indicate an infection. The area may be cleaned or flushed out with a solution. Dead skin may be removed, and a bandage applied. Antibiotics and sometimes surgery may be needed.

Surgical wound pain typically resolves as tissues heal, usually over 3 to 6 months. Pain continuing beyond that time has numerous causes, including infection and a poorly fitting preparatory prosthesis. Treatments are directed at the cause and may also include modifying the prosthesis, not wearing the prosthesis until the wound heals, and taking painkillers.

Pain due to nerve damage (neuropathic pain) is common. Usually described as a shooting or burning pain, neuropathic pain typically develops within 7 days of amputation. It can go away on its own but is often long-lasting. It can be unrelenting and severe, or intermittent. Nerves may have been damaged from an injury or when they were severed during the amputation. Treatment of neuropathic pain includes psychologic treatments, physical methods, antidepressants, and antiseizure drugs.

Painful neuromas (noncancerous overgrowths of nerve tissue) can occur in any severed nerve (from surgery or trauma) and may cause pain that feels electrical, shooting, tingling, sharp and stabbing, or prickly. The pain typically does not involve the phantom limb but can. Other symptoms of neuroma include unusual and unpleasant sensations that occur without stimulation or upon contraction of residual-limb muscles and a disagreeable sensation (dysesthesia) that occurs with light palpation of skin. The longer the neuroma is irritated, either from wearing the prosthesis or from muscle contractions, the longer it takes to go away. Doctors sometimes do MRI and/or ultrasound to confirm the diagnosis of neuroma. A severe neuroma may require surgery.

If there is no medical disorder causing the pain, massaging and light tapping combined with elevating the residual limb may help relieve the pain. If this is ineffective, mild painkillers (such as ibuprofen or acetaminophen) can be used. If pain persists, a pain management specialist may be helpful.

Sometimes pain is felt in other limbs or in the hips, spine, shoulders, or neck. This pain may occur because wearing a prosthesis makes people change the way they walk or hold their body (body alignment) or causes them to repeat movements. Regularly doing specific stretching exercises and exercises to strengthen muscles may help prevent or relieve this type of pain. A physical therapist can help design an appropriate exercise program.

Phantom pain

Most people experience pain that feels as though it were occurring in the amputated limb (phantom pain) at some time. The phantom aspect is not the pain, which is real, but the location of the pain—in a limb that has been amputated. Phantom pain usually begins within days following amputation but could be delayed months to years. Phantom pain may feel like tingling, shooting, stabbing, throbbing, burning, aching, pinching, clamping, and vise-like squeezing pain.

Phantom pain is often worse soon after the amputation, then decreases over time. For many people, phantom pain is more common when the prosthesis is not being worn, for example, at night. The risk of having this pain is reduced if both a spinal anesthetic and a general anesthetic are used during surgery.

Phantom sensation

Most people experience phantom sensation, which is the feeling that the amputated part is still present. Phantom sensation is different from phantom pain Phantom pain After an amputation, over 70% of people have pain in the residual limb (stump), which can severely limit function, impair quality of life, and significantly impede rehabilitation. Residual-limb... read more . Phantom sensation can be a particular problem with lower limb amputees during nighttime trips to the bathroom. They believe their limb is still there and take a step and fall or injure their residual limb. A protective device can be worn while sleeping to prevent injury.

Drugs Mentioned In This Article

Generic Name Select Brand Names
Advil, Advil Children's, Advil Children's Fever, Advil Infants', Advil Junior Strength, Advil Migraine, Caldolor, Children's Ibuprofen, ElixSure IB, Genpril , Ibren , IBU, Midol, Midol Cramps and Body Aches, Motrin, Motrin Children's, Motrin IB, Motrin Infants', Motrin Junior Strength, Motrin Migraine Pain, PediaCare Children's Pain Reliever/Fever Reducer IB, PediaCare Infants' Pain Reliever/Fever Reducer IB, Samson-8
7T Gummy ES, Acephen, Aceta, Actamin, Adult Pain Relief, Anacin Aspirin Free, Apra, Children's Acetaminophen, Children's Pain & Fever , Comtrex Sore Throat Relief, ED-APAP, ElixSure Fever/Pain, Feverall, Genapap, Genebs, Goody's Back & Body Pain, Infantaire, Infants' Acetaminophen, LIQUID PAIN RELIEF, Little Fevers, Little Remedies Infant Fever + Pain Reliever, Mapap, Mapap Arthritis Pain, Mapap Infants, Mapap Junior, M-PAP, Nortemp, Ofirmev, Pain & Fever , Pain and Fever , PAIN RELIEF , PAIN RELIEF Extra Strength, Panadol, PediaCare Children's Fever Reducer/Pain Reliever, PediaCare Children's Smooth Metls Fever Reducer/Pain Reliever, PediaCare Infant's Fever Reducer/Pain Reliever, Pediaphen, PHARBETOL, Plus PHARMA, Q-Pap, Q-Pap Extra Strength, Silapap, Triaminic Fever Reducer and Pain Reliever, Triaminic Infant Fever Reducer and Pain Reliever, Tylenol, Tylenol 8 Hour, Tylenol 8 Hour Arthritis Pain, Tylenol 8 Hour Muscle Aches & Pain, Tylenol Arthritis Pain, Tylenol Children's, Tylenol Children's Pain+Fever, Tylenol CrushableTablet, Tylenol Extra Strength, Tylenol Infants', Tylenol Infants Pain + Fever, Tylenol Junior Strength, Tylenol Pain + Fever, Tylenol Regular Strength, Tylenol Sore Throat, XS No Aspirin, XS Pain Reliever
quiz link

Test your knowledge

Take a Quiz!