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Overview of Cystic Kidney Disease

By

Enrica Fung

, MD, MPH, Loma Linda University School of Medicine

Last full review/revision Apr 2021| Content last modified Apr 2021
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Cystic kidney disease may be congenital or acquired. Congenital disorders may be inherited as autosomal dominant disorders or autosomal recessive disorders or have other causes (eg, sporadic mutations, chromosomal abnormalities, teratogens). Some are part of a malformation syndrome (see table Major Groups of Cystic Nephropathies Major Groups of Cystic Nephropathies Cystic kidney disease may be congenital or acquired. Congenital disorders may be inherited as autosomal dominant disorders or autosomal recessive disorders or have other causes (eg, sporadic... read more ).

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Minimal Change Disease
Spontaneous remission in patients with minimal change disease (MCD) occurs in 40% of cases. Approximately 80 to 90% of cases respond to initial therapy with corticosteroids. It is important to continue therapy for another 2 weeks after remission and change to a maintenance regimen to lower the possibility of relapse of MCD. For those patients who do not respond to corticosteroid therapy, which of the following is the most appropriate next step in treatment? 
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