Female Pelvic Pain

ByDavid H. Barad, MD, MS, Center for Human Reproduction
Reviewed/Revised Feb 2022
View Patient Education

Pelvic pain is discomfort in the lower abdomen and is a common complaint. It is considered separately from vaginal pain and from vulvar or perineal pain, which occurs in the external genitals and nearby perineal skin. The pelvic cavity also contains intestines, bladder, and lower ureters and is surrounded by muscles, connective tissue, and bones. Pelvic pain may originate from any of these structures.

Pelvic pain may be acute or chronic; pain that persists for 3 to 6 months is considered chronic.

Etiology of Pelvic Pain

Pelvic pain may originate in female reproductive organs (cervix, uterus, ovaries, fallopian tubes) or other structures in the abdomen (intestines, urinary tract, pelvic floor).

Gynecologic disorders

Some gynecologic disorders (see table Some Gynecologic Causes of Pelvic Pain) cause cyclic pelvic pain (ie, pain recurring during the same phase of the menstrual cycle). In others, pain is a unrelated to menses. Also, onset of pain (sudden or gradual) and type of pain (eg, sharp, crampy) may help identify the cause.

Overall, the most common gynecologic causes of pelvic pain include

Uterine fibroids do not usually cause pain, but pain is possible if they put pressure on surrounding structures, contribute to dysmenorrhea, or degenerate.


Nongynecologic disorders

Nongynecologic disorders that can cause pelvic pain may occur in any system located in the pelvis:

Evaluation of Pelvic Pain

Evaluation of acute pelvic pain must be expeditious because some causes (eg, ectopic pregnancy, adnexal torsion) require immediate treatment.

Pregnancy should be excluded in all patients of reproductive age regardless of menstrual or sexual history.


History of present illness should include onset, duration, location, severity, and character of pain. Relationship of pain to the menstrual cycle is noted. Important associated symptoms include vaginal bleeding or discharge, dyspareunia, fever, and symptoms of hemodynamic instability (eg, dizziness, light-headedness, syncope).

Review of systems should include the following:

  • Amenorrhea, morning sickness, or breast swelling or tenderness: Pregnancy

  • Fever, chills, or vaginal discharge: Infection

  • Abdominal pain, change in stool habits, or rectal bleeding: Gastrointestinal disorders

  • Urinary frequency, urgency, dysuria, or hematuria: Urinary disorders

Past medical history should note obstetric and gynecologic history (gravidity, parity, menstrual history, sexual history, history of sexually transmitted infections, infertility, ectopic pregnancy, pelvic inflammatory disease) and history of urinary calculi, diverticulitis, and other gastrointestinal or genitourinary conditions or cancers. Any previous abdominal or pelvic surgery should be noted.

Physical examination

The physical examination begins with review of vital signs for fever or signs of hemodynamic instability (eg, hypotension, rapid pulse) and focuses on abdominal and pelvic examinations.

The abdomen is palpated for tenderness, masses, and peritoneal signs. Rectal examination is done to check for tenderness, masses, and occult blood. Location of pain and any associated findings may provide clues to the cause (see table Some Clues to Diagnosis of Pelvic Pain).

Pelvic examination includes inspection of external genitals, speculum examination, and bimanual examination. The cervix is inspected for discharge or lesions. Bimanual examination should assess cervical motion tenderness, adnexal masses or tenderness, and uterine enlargement or tenderness. If ectopic pregnancy is suspected, pressure should not be applied to an adnexal mass because pressure may cause rupture.

Red flags

The following findings are of particular concern:

  • Syncope or hemorrhagic shock (eg, tachycardia, hypotension)

  • Peritoneal signs (rebound, rigidity, guarding)

  • Postmenopausal vaginal bleeding

  • Fever or chills

  • Sudden severe pain with nausea, vomiting, or diaphoresis

Interpretation of findings

Acuity and severity of pelvic pain and its relationship to menstrual cycles can suggest the most likely causes (see table Some Gynecologic Causes of Pelvic Pain). Quality and location of pain and associated findings also provide clues (see table Some Clues to Diagnosis of Pelvic Pain). However, findings may be nonspecific. For example, endometriosis can result in a wide variety of findings.



All patients with pelvic pain should have

  • Pregnancy test

  • Urinalysis

If a patient is pregnant and has pain or bleeding, ectopic pregnancy is assumed until excluded by ultrasonography or, if ultrasonography is unclear, by other tests. If a suspected pregnancy may be < 5 weeks, a serum pregnancy test should be done; a urine pregnancy test may not be sensitive enough to rule out pregnancy that early in gestation. If urinary symptoms are present, urinalysis is a fast, simple test done to rule out many common causes of pelvic pain (eg, cystitis, urinary calculi).

Other testing depends on which disorders are clinically suspected. If a patient cannot be adequately examined (eg, because of pain) or if a mass is suspected, pelvic ultrasonography is done. If the cause of severe or persistent pain remains unidentified and a serious cause (eg, ruptured ectopic pregnancy, peritonitis) is suspected, laparoscopy or laparotomy may be done.

Transvaginal pelvic ultrasonography can be a useful adjunct to pelvic examination; it can better define a mass or help diagnose a pregnancy after 5 weeks gestation (ie, 1 week after a missed menstrual period). For example, a positive pregnancy test plus no evidence of an intrauterine pregnancy support a diagnosis of ectopic pregnancy.

Treatment of Pelvic Pain

Treatment for pain during pregnancy is based on maternal and fetal considerations.

The underlying disorder is treated when possible.

Pelvic pain in nonpregnant patients is initially treated with oral nonsteroidal anti-inflammatory drugs (NSAIDs). Patients who do not respond well to one NSAID may respond to another.

Pain related to the menstrual cycle (eg, dysmenorrhea, endometriosis) may be treated with hormonal contraceptives.

Musculoskeletal or myofascial pain requires rest, heat, physical therapy, analgesics or other drugs.

If patients have intractable pain unresponsive to any of the above measures, hysterectomy may be offered as a last option.

Geriatrics Essentials

Pelvic pain symptoms in older women may be vague. Careful review of systems with attention to bowel and bladder function is essential.

In older women, common causes of pelvic pain may be different because some disorders that cause pelvic pain or discomfort become more common as women age, particularly after menopause. These disorders include

A general medical history and obstetric and gynecologic history should be obtained. A sexual history should also be obtained; clinicians often do not realize that many women remain sexually active throughout their life.

Acute loss of appetite, weight loss, dyspepsia, bloating, or a sudden change in bowel habits may be signs of ovarian or uterine cancer and requires thorough clinical evaluation.

Key Points

  • Pelvic pain is common and may have a gynecologic or nongynecologic cause.

  • Pregnancy should be ruled out in all patients of reproductive age.

  • Quality, acuity, severity, and location of pain and its relationship to the menstrual cycle can suggest the most likely causes.

Test your KnowledgeTake a Quiz!
Download the free Merck Manual App iOS ANDROID
Download the free Merck Manual App iOS ANDROID
Download the free Merck Manual App iOS ANDROID