The mediastinum contains the heart, trachea, esophagus, thymus, and lymph nodes. Nearly all mediastinoscopies are used to diagnose the cause of enlarged lymph nodes deep in the chest or to evaluate how far lung cancer has spread before chest surgery (thoracotomy) is done.
Mediastinoscopy is done in an operating room with the person under general anesthesia. A small incision is made in the notch just above the breastbone (sternum). The instrument then is passed down into the chest in front of the windpipe, allowing the doctor to observe the contents of the mediastinum next to the windpipe and to obtain specimens for diagnostic tests if necessary.
Mediastinotomy gives direct access to structures that are inaccessible by mediastinoscopy.
Although mediastinoscopy and mediastinotomy are usually very safe, occasionally complications develop, including reactions to anesthetic drugs, infection, and injury to the lung causing air to leak into the pleural space (pneumothorax). Rarer but more serious complications include bleeding caused by damage to one of the large blood vessels around the heart and injury to a nerve in the chest (which can cause hoarseness).