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Acute Abdominal Pain


Jonathan Gotfried

, MD, Lewis Katz School of Medicine at Temple University

Reviewed/Revised Jan 2022 | Modified Sep 2022
Topic Resources

Abdominal pain is common and often minor. Severe abdominal pain that comes on quickly, however, almost always indicates a significant problem. The pain may be the only sign of the need for surgery and must be attended to swiftly. Older adults and those who have HIV infection or who are taking immunosuppressants (including corticosteroids) may have less abdominal pain than younger/healthy adults with a similar disorder, and, even if the condition is serious, the pain may develop more gradually. Young children, especially newborns and infants, may develop abdominal pain but are unable to communicate the reason for their distress.

Types of Abdominal Pain

There are different types of abdominal pain depending on the structures involved.

Visceral pain comes from the organs within the abdominal cavity (which are called the viscera). The viscera's nerves do not respond to cutting, tearing, or inflammation. Instead, the nerves respond to the organ being stretched (as when the intestine is expanded by gas) or surrounding muscles contract. Visceral pain is typically vague, dull, and nauseating. It may be hard to pinpoint. Upper abdominal pain results from disorders in organs such as the stomach, duodenum, liver, and pancreas. Midabdominal pain (near the navel) results from disorders of structures such as the small intestine, upper part of the colon, and appendix. Lower abdominal pain results from disorders of the lower part of the colon and organs in the genitourinary tract.

Somatic pain comes from the membrane (peritoneum) that lines the abdominal cavity (peritoneal cavity). Unlike nerves in the visceral organs, nerves in the peritoneum respond to cutting and irritation (such as from blood, infection, chemicals, or inflammation). Somatic pain is sharp and fairly easy to pinpoint.

Referred pain is pain that is felt in an area that is distant from the source ( see Figure: What Is Referred Pain? What Is Referred Pain? What Is Referred Pain? ). For example, a person who has gallbladder disease may feel pain in the shoulder blade. The source of the pain is the gallbladder, which is located in the abdomen, but the pain is felt in the shoulder.

What Is Referred Pain?

Pain felt in one area of the body does not always represent where the problem is because the pain may be referred there from another area. For example, pain produced by a heart attack may feel as if it is coming from the arm because sensory information from the heart and the arm converge on the same nerve pathways in the spinal cord.

What Is Referred Pain?


Peritonitis is inflammation of the peritoneal cavity. It is very painful and almost always signals a very serious or life-threatening disorder. It can result from any abdominal problem in which the organs are inflamed or infected. Common examples include appendicitis Appendicitis Appendicitis is inflammation and infection of the appendix. Often a blockage inside the appendix causes the appendix to become inflamed and infected. Abdominal pain, nausea, and fever are common... read more , diverticulitis Diverticulitis Diverticulitis is inflammation of one or more balloon-like sacs (diverticula). Infection may or may not develop. Diverticulitis usually affects the large intestine (colon). Left lower abdominal... read more Diverticulitis , and pancreatitis Overview of Pancreatitis Pancreatitis is inflammation of the pancreas. The pancreas is a leaf-shaped organ about 5 inches (about 13 centimeters) long. It is surrounded by the lower edge of the stomach and the first... read more . Also, blood and body fluids (such as intestinal contents or urine) are very irritating when they leak into the peritoneal cavity and can cause peritonitis. Disorders that cause blood and body fluids to leak include spontaneous organ rupture (such as a perforated intestine Perforation of the Digestive Tract Any of the hollow digestive organs may become perforated (punctured), which causes a release of intestinal contents and can lead to sepsis (a life-threatening infection of the bloodstream) and... read more or ruptured ectopic pregnancy Ectopic Pregnancy Ectopic pregnancy is attachment (implantation) of a fertilized egg in an abnormal location, such as a fallopian tube. In an ectopic pregnancy, the fetus cannot survive. Women with an ectopic... read more ) and severe abdominal injury. People who have fluid in the peritoneal cavity (the fluid is called ascites Ascites Ascites is the accumulation of protein-containing (ascitic) fluid within the abdomen. Many disorders can cause ascites, but the most common is high blood pressure in the veins that bring blood... read more ) are at risk of developing an infection. Such an infection is called spontaneous bacterial peritonitis.

Once peritonitis has been present for a number of hours, the inflammation causes fluid to leak into the abdominal cavity. The person may then develop dehydration and go into shock. Inflammatory substances released into the bloodstream may affect various organs, causing severe lung inflammation, kidney failure, liver failure, and other problems. Without successful treatment, people may die.

Causes of Acute Abdominal Pain

Pain can arise from many causes, including infection, inflammation, ulcers, perforation or rupture of organs, muscle contractions that are uncoordinated or blocked by an obstruction, and blockage of blood flow to organs.

Immediately life-threatening disorders, which require rapid diagnosis and surgery, include

Serious disorders that are nearly as urgent include

Sometimes, disorders outside the abdomen cause abdominal pain. Examples include heart attack, pneumonia, and twisting of a testis (testicular torsion). Less common problems outside the abdomen that cause abdominal pain include diabetic ketoacidosis, porphyria, sickle cell disease, and certain bites and poisons (such as a black widow spider bite, heavy metal or methanol poisoning, and some scorpion stings).

Abdominal pain in newborns, infants, and young children has numerous causes not encountered in adults (see table Abdominal Pain in Newborns, Infants, and Young Children Abdominal Pain in Newborns, Infants, and Young Children Abdominal Pain in Newborns, Infants, and Young Children ).


Evaluation of Acute Abdominal Pain

The following information can help people decide when a doctor's evaluation is needed and help them know what to expect during the evaluation.

Warning signs

In people with acute abdominal pain, certain symptoms and characteristics are cause for concern. They include

  • Severe pain

  • Signs of shock (for example, a rapid heart rate, low blood pressure, sweating, and confusion)

  • Signs of peritonitis (for example, constant pain that doubles the person over and/or pain that worsens with gentle touching or with bumping the bed)

  • Swelling of the abdomen

When to see a doctor

People who have warning signs should go to the hospital right away. People who have no warning signs should see a doctor within a day.

What the doctor does

Doctors ask questions about the person's symptoms and medical history and do a physical examination. What doctors find during the history and physical examination helps them decide what, if any, tests need to be done. Doctors follow the same process whether they are evaluating mild or severe pain, although a surgeon may be involved early on in the evaluation of severe abdominal pain.

When taking the medical history ( see Table: History in People With Acute Abdominal Pain History in People With Acute Abdominal Pain History in People With Acute Abdominal Pain ), doctors ask questions about the pain's location ( see Figure: Causes of Abdominal Pain by Location Causes of Abdominal Pain by Location Causes of Abdominal Pain by Location ) and characteristics, whether the person has had similar symptoms in the past, and what other symptoms the person has along with the abdominal pain. Symptoms such as heartburn, nausea, vomiting, diarrhea, constipation, jaundice, blood in the stool or urine, coughing up blood, and weight loss help guide the doctor's evaluation. Doctors ask questions about drugs taken, including prescription and illicit drugs as well as alcohol.

Doctors ask questions about known medical conditions and previous abdominal surgeries. Women are asked whether they are or could be pregnant.

When conducting a physical examination, doctors first note the person's general appearance. A comfortable-appearing person rarely has a serious problem, unlike one who is anxious, pale, sweating, or in obvious pain. The focus of the examination is the abdomen, and doctors inspect, tap, and touch (a process called palpation) the abdominal area. They usually examine the rectum and pelvis (for women) to locate tenderness, masses, and blood.

Doctors touch the whole abdomen gently to detect areas of particular tenderness, as well as the presence of guarding, rigidity, rebound, and any masses. Guarding is when a person involuntarily contracts the abdominal muscles when the doctor touches the abdomen. Rigidity is when the abdominal muscles stay firmly contracted even when the doctor is not touching them. Rebound is when a person flinches in pain as the doctor's hand is briskly withdrawn. Guarding, rigidity, and rebound are signs of peritonitis.


Causes of Abdominal Pain by Location

Causes of Abdominal Pain by Location


Sometimes, people have findings so significant that doctors realize right away that they need surgery. Doctors try not to delay surgery on such people by doing tests. However, more often, doctors must do tests to help choose among several different causes suggested by the person's symptoms and physical examination results. Doctors select tests based on what they suspect:

  • Urine pregnancy test for all girls and women of childbearing age

  • Imaging tests based on suspected diagnosis

Treatment of Acute Abdominal Pain

The specific cause of the pain is treated. Until recently, doctors thought that it was not wise to give pain relievers to people with severe abdominal pain until a diagnosis was made because the pain reliever might mask important symptoms. However, pain relievers are now sometimes given, usually in low doses, while tests are in progress.

Key Points

  • Doctors look first for any life-threatening causes for the pain.

  • Doctors rule out pregnancy in girls and women of childbearing age.

  • Blood tests rarely identify a specific cause of acute abdominal pain.

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