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Swelling During Late Pregnancy
As pregnancy progresses, fluid may accumulate in tissues, usually in the feet, ankles, and legs, causing them to swell and appear puffy. This condition is called edema. Occasionally, the face and hands also swell. Some fluid accumulation during pregnancy is normal, particularly during the 3rd trimester. It is called physiologic edema.
Fluid accumulates during pregnancy because the adrenal glands produce more of the hormones that make the body retain fluids (aldosterone and cortisol). Fluid also accumulates because the enlarging uterus interferes with blood flow from the legs to the heart. As a result, fluid backs up in the veins of the legs and seeps out into the surrounding tissues.
Less commonly, swelling during pregnancy results from a disorder (see Table: Some Causes and Features of Swelling During Late Pregnancy). However, such disorders are often serious. They include
In deep vein thrombosis, blood clots form in veins located deep within part of the body, often in the legs. Pregnancy increases the risk of this disorder in several ways. During pregnancy, the body produces more of the proteins that help blood clot (clotting factors), probably intended to prevent too much bleeding during childbirth. Also, changes during pregnancy cause blood to back up in veins, making clots more likely to form. If the pregnant woman is less mobile, blood is even more likely to back up in leg veins and clot. The clots may interfere with blood flow. If a blood clot breaks loose, it can travel through the bloodstream to the lungs, blocking blood flow there. This blockage (called pulmonary embolism) is life threatening.
In preeclampsia, blood pressure and protein levels in urine increase during pregnancy. Fluids may accumulate, causing swelling in the face, hands, or feet and weight gain. If severe, preeclampsia can damage organs, such as the brain, kidneys, lungs, or liver, and cause problems in the baby.
In cellulitis, bacteria infect the skin and tissues under the skin, sometimes causing swelling with redness and tenderness. Cellulitis most commonly affects the legs but may occur anywhere.
The risk of deep vein thrombosis and preeclampsia is increased by various conditions (risk factors).
For deep vein thrombosis, risk factors include
For preeclampsia, risk factors include
Doctors must rule out deep vein thrombosis, preeclampsia, cellulitis, and other possible causes before they can diagnose physiologic edema.
In pregnant women with swollen legs, the following symptoms are cause for concern:
Blood pressure that is 140/90 mm Hg or higher
Swelling in only one leg or calf, particularly if the area is warm, red, and/or tender or fever is present
Swelling in the hands
Swelling that suddenly increases
Confusion, difficulty breathing, changes in vision, shaking (tremor), a seizure, sudden abdominal pain, or a sudden headache—symptoms that may be caused by preeclampsia
Doctors first ask questions about the swelling and other symptoms and about the medical history. Doctors then do a physical examination. What they find during the history and physical examination often suggests a cause of the swelling and the tests that may need to be done (see Table: Some Causes and Features of Swelling During Late Pregnancy).
Doctors ask when the swelling started, how long it has been present, and whether any activity (such as lying on the left side) lessens or worsens it. Lying on the left side decreases physiologic edema. Doctors also ask about conditions that increase the risk of developing deep vein thrombosis and preeclampsia.
Women are asked about other symptoms, which may suggest a cause. They are asked whether they have ever had deep vein thrombosis, pulmonary embolism, preeclampsia, or high blood pressure.
During the physical examination, doctors look for evidence of a serious cause. To check for symptoms of preeclampsia, doctors measure blood pressure and may check the woman's reflexes and look at the back of her eyes with an ophthalmoscope (a handheld device that resembles a small flashlight).
Some Causes and Features of Swelling During Late Pregnancy
If deep vein thrombosis is suspected, Doppler ultrasonography of the affected leg is done. This test can show disturbances in blood flow caused by blood clots in the leg veins.
If preeclampsia is suspected, the protein level is measured in a urine sample. High blood pressure plus a high protein level in urine indicates preeclampsia. If the diagnosis is unclear, the woman is asked to collect her urine for 24 hours, and protein is measured in that volume of urine. This measurement is more accurate.
When swelling results from a disorder, that disorder is treated.
The swelling that occurs normally during pregnancy can be reduced by doing the following:
Lying on the left side, which moves the uterus off the large vein that returns blood to the heart (inferior vena cava)
Resting frequently with the legs elevated
Wearing elastic support stockings
Wearing loose clothing that does not restrict blood flow, particularly in the legs (for example, not wearing socks or stockings that have tight bands around the ankles or calves)
Some swelling in the legs and ankles is normal (physiologic) during pregnancy and occurs during the 3rd trimester.
Doctors can identify serious causes of swelling based on results of a physical examination, blood pressure measurement, urine tests, and sometimes ultrasonography.
If pregnancy itself is the cause, swelling can be reduced by lying on the left side, elevating the legs periodically, and wearing support stockings.
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