Learning disorders are considered a type of neurodevelopmental disorder. Neurodevelopmental disorders are neurologically based conditions that appear early in childhood, typically before school entry. These disorders impair development of personal, social, academic, and/or occupational functioning and typically involve difficulties with the acquisition, retention, or application of specific skills or sets of information. The disorders may involve dysfunction in attention, memory, perception, language, problem-solving, or social interaction. Other common neurodevelopmental disorders include attention-deficit/hyperactivity disorder Attention-Deficit/Hyperactivity Disorder (ADD, ADHD) Attention-deficit/hyperactivity disorder (ADHD) is a syndrome of inattention, hyperactivity, and impulsivity. The 3 types of ADHD are predominantly inattentive, predominantly hyperactive/impulsive... read more , autism spectrum disorders Autism Spectrum Disorders Autism spectrum disorders are neurodevelopmental disorders characterized by impaired social interaction and communication, repetitive and stereotyped patterns of behavior, and uneven intellectual... read more , and intellectual disability Intellectual Disability Intellectual disability is characterized by significantly subaverage intellectual functioning (often expressed as an intelligence quotient < 70 to 75) combined with limitations of adaptive... read more .
Specific learning disorders affect the ability to
Understand or use spoken language
Understand or use written language
Understand and use numbers and reason using mathematical concepts
Focus attention on a task
Thus, these disorders involve problems in reading, mathematics, spelling, written expression or handwriting, and understanding or using verbal and nonverbal language (see table Common Specific Learning Disorders ). Most learning disorders are complex or mixed, with deficits in more than one system.
Although the total number of children in the US with learning disorders is unknown, in the 2019-2020 school year, 7.3 million students (or 14% of all public school students) ages 3 to 21 in the US received special education services under the Individuals with Disabilities Education Act (IDEA). Among students receiving special education services, 33% (or about 5% of all students) had specific learning disabilities (1 General references Learning disorders are conditions that cause a discrepancy between potential and actual levels of academic performance as predicted by the person’s intellectual abilities. Learning disorders... read more ). Boys with learning disorders outnumber girls 5:1. Although formal diagnoses may help some children get assistance, characterizing different capabilities as disorders risks medicalizing them as somehow pathological. The important thing is to identify people who need different or additional help learning and provide access to the assistance they need.
Learning disorders may be congenital or acquired. No single cause has been defined, but neurologic deficits are presumed to be involved whether or not other neurologic manifestations (ie, apart from the learning disorder) are present. Genetic influences are often implicated. Other possible causes include
Complications during pregnancy or delivery (eg, spotting, toxemia, prolonged labor, precipitous delivery)
Neonatal problems (eg, prematurity Preterm Infants An infant born before 37 weeks gestation is considered preterm. Prematurity is defined by the gestational age at which infants are born. Previously, any infant weighing < 2.5 kg was termed... read more , low birth weight, severe jaundice Neonatal Hyperbilirubinemia Jaundice is a yellow discoloration of the skin and eyes caused by hyperbilirubinemia (elevated serum bilirubin concentration). The serum bilirubin level required to cause jaundice varies with... read more , perinatal asphyxia, postmaturity Postterm Infants A postterm infant is an infant born after 42 weeks gestation. The cause of postmaturity is generally unknown, but previous postterm delivery increases the risk 2- to 3-fold. Postmaturity may... read more , respiratory distress)
Potential postnatal factors include exposure to environmental toxins (eg, lead Lead Poisoning Lead poisoning often causes minimal symptoms at first but can cause acute encephalopathy or irreversible organ damage, commonly resulting in cognitive deficits in children. Diagnosis is by whole... read more ), central nervous system infections, cancers and their treatments, trauma, undernutrition Overview of Undernutrition Undernutrition is a form of malnutrition. (Malnutrition also includes overnutrition.) Undernutrition can result from inadequate ingestion of nutrients, malabsorption, impaired metabolism, loss... read more , and severe social isolation or deprivation. Adverse childhood experiences (ACEs) such as abuse and maltreatment have been particularly associated with executive function problems (2 General references Learning disorders are conditions that cause a discrepancy between potential and actual levels of academic performance as predicted by the person’s intellectual abilities. Learning disorders... read more ).
Common Specific Learning Disorders
Problems with reading
Problems with sound analysis and memory
Problems with visual recognition of forms and structures of words
Dysgraphia (impairment in written expression)
Problems with spelling, written expression, or handwriting
Dyscalculia (impairment in mathematics)
Problems with mathematics and difficulties with problem-solving
Problems due to disturbances in mathematical reasoning
Disturbances in basic concept formation and inability to acquire computational skills
Anomic aphasia (dysnomia)
Difficulty recalling words and information from memory on demand
1. National Center for Educational Statistics: Students with disabilities. In The Condition of Education 2021.
2. Lund JI, Toombs E, Radford A, et al: Adverse childhood experiences and executive function difficulties in children: A systematic review. Child Abuse Negl 106:104485, 2020. doi: 10.1016/j.chiabu.2020.104485
Symptoms and Signs of Learning Disorders
Children with learning disorders typically have at least average intelligence, although such disorders can occur in children with lower cognitive function as well.
Symptoms and signs of severe learning disorders may manifest at an early age, but most mild to moderate learning disorders are not recognized until school age, when the rigors of academic learning are encountered.
Affected children may have trouble learning the alphabet and may be delayed in paired associative learning (eg, color naming, labeling, counting, letter naming). Speech perception may be limited, language may be learned at a slower rate, and vocabulary may be decreased. Affected children may not understand what is read, have very messy handwriting or hold a pencil awkwardly, have trouble organizing or beginning tasks or retelling a story in sequential order, or confuse math symbols and misread numbers.
Executive function impairments
Disturbances or delays in expressive language or listening comprehension are predictors of academic problems beyond the preschool years. Memory may be defective, including short-term and long-term memory, memory use (eg, rehearsal), and verbal recall or retrieval.
Problems may occur in conceptualizing, abstracting, generalizing, reasoning, and organizing and planning information for problem solving. People with executive function problems often have difficulty organizing and completing assignments.
Visual perception and auditory processing problems may occur; they include difficulties in spatial cognition and orientation (eg, object localization, spatial memory, awareness of position and place), visual attention and memory, and sound discrimination and analysis.
Some children with learning disabilities have difficulty following social conventions (eg, taking turns, standing too close to the listener, not understanding jokes); these difficulties are often components of mild autism spectrum disorders Autism Spectrum Disorders Autism spectrum disorders are neurodevelopmental disorders characterized by impaired social interaction and communication, repetitive and stereotyped patterns of behavior, and uneven intellectual... read more as well.
Short attention span, motor restlessness, fine motor problems (eg, poor printing and copying), and variability in performance and behavior over time are other early signs.
Difficulties with impulse control, non–goal-directed behavior and overactivity, discipline problems, aggressiveness, withdrawal and avoidance behavior, excessive shyness, and excessive fear may occur. Learning disabilities and attention-deficit/hyperactivity disorder Attention-Deficit/Hyperactivity Disorder (ADD, ADHD) Attention-deficit/hyperactivity disorder (ADHD) is a syndrome of inattention, hyperactivity, and impulsivity. The 3 types of ADHD are predominantly inattentive, predominantly hyperactive/impulsive... read more (ADHD) often occur together.
Diagnosis of Learning Disorders
Cognitive, educational, medical, and psychologic evaluations
Children with learning disorders are typically identified when a discrepancy is recognized between academic potential and academic performance. Speech and language, cognitive, educational, medical, and psychologic evaluations are necessary for determining deficiencies in skills and cognitive processes. Social and emotional-behavioral evaluations are also necessary for planning treatment and monitoring progress.
Cognitive evaluation typically includes verbal and nonverbal intelligence testing and is usually done by a school psychologist. Psychoeducational testing may be helpful in describing the child’s preferred manner of processing information (eg, holistically or analytically, visually or aurally). Neuropsychologic assessment is particularly useful in children with known central nervous system injury or illness to map the areas of the brain that correspond to specific functional strengths and weaknesses. Speech and language evaluations establish integrity of comprehension and language use, phonologic processing, and verbal memory and can also assess pragmatic (social) language.
Educational assessment and performance evaluation by teachers’ observations of classroom behavior and determination of academic performance are essential. Reading evaluations measure abilities in word decoding and recognition, comprehension, and fluency. Writing samples should be obtained to evaluate spelling, syntax, and fluency of ideas. Mathematical ability should be assessed in terms of computation skills, knowledge of operations, understanding of concepts, and interpretation of "word problems."
Medical evaluation includes a detailed family history, the child’s medical history, a physical examination, and a neurologic or neurodevelopmental examination to look for underlying disorders. Although infrequent, physical abnormalities and neurologic signs may indicate medically treatable causes of learning disabilities. Gross motor coordination problems may indicate neurologic deficits or neurodevelopmental delays. Developmental level is evaluated according to standardized criteria.
Psychologic evaluation helps identify ADHD, conduct disorder, anxiety disorders, depression, and poor self-esteem, which frequently accompany and must be differentiated from learning disabilities. Attitude toward school, motivation, peer relationships, and self-confidence are assessed.
Diagnosis of learning disorders is made clinically based on criteria in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), and requires evidence that at least one of the following has been present for ≥ 6 months despite targeted intervention:
Inaccurate, slow and/or effortful word reading
Difficulty understanding the meaning of written material
Difficulty writing (eg, multiple grammar and punctuation errors; ideas not expressed clearly)
Difficulty mastering number sense (eg, understanding the relative magnitude and relationship of numbers; in older children, difficulty doing simple calculations)
Difficulty with mathematical reasoning (eg, using mathematical concepts to solve problems)
Skills must be substantially below the level expected for the child's age and also significantly impair performance at school or in daily activities. Also, the difficulties should not be better accounted for by intellectual disability Intellectual Disability Intellectual disability is characterized by significantly subaverage intellectual functioning (often expressed as an intelligence quotient < 70 to 75) combined with limitations of adaptive... read more or other neurodevelopmental disorders.
Treatment of Learning Disorders
Medical, behavioral, and psychologic therapy
Occasionally drug therapy
Treatment of learning disorders centers on educational management but may also involve medical, behavioral, and psychologic therapy. Effective teaching programs may take a remedial, compensatory, or strategic (ie, teaching the child how to learn) approach. A mismatch of instructional method and a child’s learning disorder and learning preference aggravates the disability.
Some children require specialized instruction in only one area while they continue to attend regular classes. Other children need separate and intense educational programs. Optimally and as required by US law, affected children should participate as much as possible in inclusive classes with peers who do not have learning disabilities.
Drugs minimally affect academic achievement, intelligence, and general learning ability, although certain drugs (eg, psychostimulants Stimulant drugs Attention-deficit/hyperactivity disorder (ADHD) is a syndrome of inattention, hyperactivity, and impulsivity. The 3 types of ADHD are predominantly inattentive, predominantly hyperactive/impulsive... read more , such as methylphenidate and several amphetamine preparations) may enhance attention and concentration, allowing children to respond more efficiently to instruction.
Many popular remedies and therapies (eg, eliminating food additives, using antioxidants or megadoses of vitamins, patterning by sensory stimulation and passive movement, sensory integrative therapy through postural exercises, auditory nerve training, optometric training to remedy visual-perceptual and sensorimotor coordination processes) are unproved.
The following are English-language resources that may be useful. Please note that THE MANUAL is not responsible for the content of these resources.
Individuals with Disabilities Education Act (IDEA): A US law that makes available free appropriate public education to eligible children with disabilities and ensures special education and related services to those children
Learning Disabilities Association of America (LDA): An organization providing educational, support, and advocacy resources for people with learning disabilities
Drugs Mentioned In This Article
|Drug Name||Select Trade|
|Adhansia XR, Aptensio XR, Concerta, Cotempla XR, Daytrana, Jornay, Metadate CD, Metadate ER, Methylin, QuilliChew ER, Quillivant XR, RELEXXII, Ritalin, Ritalin LA, Ritalin SR|
|Adzenys, Adzenys XR, Dyanavel XR, Evekeo|