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Introduction to Bullous Diseases

By

Daniel M. Peraza

, MD, Geisel School of Medicine at Dartmouth University

Last full review/revision Sep 2020| Content last modified Sep 2020
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Bullae are elevated, fluid-filled blisters ≥ 10 mm in diameter.

The autoimmune bullous diseases include

Although epidermolysis bullosa acquisita is thought to be an autoimmune disease, epidermolysis bullosa Epidermolysis Bullosa Epidermolysis bullosa is a group of 4 very rare genetic diseases and their subtypes. Epithelial fragility and easy blistering of skin and mucous membranes usually manifest at birth or in infancy... read more Epidermolysis Bullosa is a group of inherited diseases in which epithelial adhesion protein defects lead to epithelial fragility and bullae formation.

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Lichen Planus
A 65-year-old man comes to the office because he has had an itchy rash for the past 6 weeks that is purple in color on the flexor aspect of each wrist. On physical examination, the lesions are flat and smooth. Biopsy is performed, and lichen planus is confirmed. Which of the following laboratory studies should be done? 
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