Complete examination of all systems is essential to detect peripheral and systemic effects of cardiac disorders and evidence of noncardiac disorders that might affect the heart. Examination includes the following:
Vital sign measurement
Pulse palpation and auscultation
Chest inspection, and palpation
Lung examination, including percussion, palpation, and auscultation
Extremity and abdomen examination
Cardiac auscultation Cardiac Auscultation Auscultation of the heart requires excellent hearing and the ability to distinguish subtle differences in pitch and timing. Hearing-impaired health care practitioners can use amplified stethoscopes... read more is discussed in a separate topic. Despite the ever-increasing use of cardiac imaging, bedside auscultation remains useful as it is always available and can be repeated as often as desired without cost.
Examination also includes the collection of other patient data.
Vital signs include
Heart rate and rhythm
Additional data often obtained along with vital signs include patient weight and peripheral oxygen saturation (SpO2).
Blood pressure (BP) is measured in both arms and, for suspected congenital cardiac disorders or peripheral vascular disorders, in both legs. The bladder of an appropriately sized cuff encircles 80% of the limb’s circumference, and the bladder’s width is 40% of the circumference. The first sound heard as the mercury column falls is systolic pressure; disappearance of the sound is diastolic pressure (5th-phase Korotkoff sound). Up to a 15 mm Hg pressure differential between the right and left arms is normal; a greater differential suggests a vascular abnormality (eg, dissecting thoracic aorta) or a peripheral vascular disorder. Leg pressure is usually 20 mm Hg higher than arm pressure. To obtain an accurate blood pressure measurement, the patient should
Be seated in a chair (not on the examination table) for > 5 minutes, feet on floor, back supported
Have the limb supported at heart level with no clothing covering the area of cuff placement
Abstain from exercising, consuming caffeine, or smoking for at least 30 minutes before the measurement is taken
Heart rate and rhythm are assessed by palpating the carotid or radial pulse or by cardiac auscultation if arrhythmia Overview of Arrhythmias The normal heart beats in a regular, coordinated way because electrical impulses generated and spread by myocytes with unique electrical properties trigger a sequence of organized myocardial... read more is suspected; some heartbeats during arrhythmias may be audible but do not generate a palpable pulse.
Respiratory rate, if abnormal, may indicate cardiac decompensation or a primary lung disorder. The rate increases in patients with heart failure Heart Failure (HF) Heart failure (HF) is a syndrome of ventricular dysfunction. Left ventricular (LV) failure causes shortness of breath and fatigue, and right ventricular (RV) failure causes peripheral and abdominal... read more or anxiety Overview of Anxiety Disorders Everyone periodically experiences fear and anxiety. Fear is an emotional, physical, and behavioral response to an immediately recognizable external threat (eg, an intruder, a car spinning on... read more and decreases or becomes intermittent in the moribund. Shallow, rapid respirations may indicate pleuritic pain.
Temperature may be elevated by acute rheumatic fever Rheumatic Fever Rheumatic fever is a nonsuppurative, acute inflammatory complication of group A streptococcal pharyngeal infection, causing combinations of arthritis, carditis, subcutaneous nodules, erythema... read more or cardiac infection (eg, endocarditis Infective Endocarditis Infective endocarditis is infection of the endocardium, usually with bacteria (commonly, streptococci or staphylococci) or fungi. It may cause fever, heart murmurs, petechiae, anemia, embolic... read more ). After a myocardial infarction Acute Myocardial Infarction (MI) Acute myocardial infarction is myocardial necrosis resulting from acute obstruction of a coronary artery. Symptoms include chest discomfort with or without dyspnea, nausea, and/or diaphoresis... read more , low grade fever is very common. Other causes are sought only if fever persists > 72 hours.
Weight is collected at each clinic visit with the patient on a standing scale and, ideally, while wearing a similar amount of clothing. In patients with heart failure, weight gain may indicate hypervolemia, while weight loss may indicate cardiac cachexia (unintentional, non-edematous weight loss of > 5% within the last 12 months— 1 General reference Complete examination of all systems is essential to detect peripheral and systemic effects of cardiac disorders and evidence of noncardiac disorders that might affect the heart. Examination... read more ). History History Symptoms or the physical examination may suggest a cardiovascular disorder. For confirmation, selected noninvasive and invasive cardiac tests are usually done. A thorough history is fundamental... read more and additional findings from the physical examination (jugular veins Neck veins Complete examination of all systems is essential to detect peripheral and systemic effects of cardiac disorders and evidence of noncardiac disorders that might affect the heart. Examination... read more , lung and extremity examinations) are required to determine whether weight changes are related to changes in volume status and/or amount of muscle or fat.
Peripheral arterial oxygen saturation (SpO2)is obtained. Pulse oximetry measures the oxygen saturation of hemoglobin in arterial blood (SpO2) and serves as a rapid, noninvasive estimation of tissue oxygenation. Pulse oximetry is obtained by using a probe attached to a finger or earlobe. Overall consensus is that SpO2 ≥ 95% is normal, whereas values < 95% suggest hypoxemia. A notable exception to this cutoff value is in patients with chronic obstructive pulmonary disease Chronic Obstructive Pulmonary Disease (COPD) Chronic obstructive pulmonary disease (COPD) is airflow limitation caused by an inflammatory response to inhaled toxins, often cigarette smoke. Alpha-1 antitrypsin deficiency and various occupational... read more ; in these patients, the target SpO2 is 88 to 92%. When hypoxemia is present, potential cardiac etiologies include pulmonary edema Pulmonary Edema Pulmonary edema is acute, severe left ventricular failure with pulmonary venous hypertension and alveolar flooding. Findings are severe dyspnea, diaphoresis, wheezing, and sometimes blood-tinged... read more in patients with heart failure and right-to-left intracardiac shunts (a patent foramen ovale in patients with pulmonary hypertension Pulmonary Hypertension Pulmonary hypertension is increased pressure in the pulmonary circulation. It has many secondary causes; some cases are idiopathic. In pulmonary hypertension, pulmonary vessels may become constricted... read more , congenital heart disease including tetralogy of Fallot Tetralogy of Fallot Tetralogy of Fallot consists of 4 features: a large ventricular septal defect, right ventricular outflow tract obstruction and pulmonic valve stenosis, right ventricular hypertrophy, and over-riding... read more ).
Ankle-brachial index (ABI)
The ankle-brachial index (ABI) is the ratio of systolic blood pressure (BP) in the ankle to that in the arm. With the patient recumbent, the ankle blood pressure is measured in both the dorsalis pedis and posterior tibial artery, and the arm blood pressure is measured in both arms at the brachial artery. The index is calculated for each lower extremity by dividing the higher of the dorsalis pedis or posterior tibial pressure in that extremity by the higher of the 2 brachial artery systolic pressures. This ratio is normally > 1. A Doppler probe may be used to measure blood pressure at the ankle if the pedal pulses are not easily palpable.
A low (≤ 0.90) ankle-brachial index suggests peripheral arterial disease Peripheral Arterial Disease Peripheral arterial disease (PAD) is atherosclerosis of the extremities (virtually always lower) causing ischemia. Mild PAD may be asymptomatic or cause intermittent claudication; severe PAD... read more , which can be classified as mild (index 0.71 to 0.90), moderate (0.41 to 0.70), or severe (≤ 0.40). A high index (> 1.30) may indicate noncompressible leg vessels, as may occur in conditions that are associated with blood vessel calcification, for example, diabetes Diabetes Mellitus (DM) Diabetes mellitus is impaired insulin secretion and variable degrees of peripheral insulin resistance leading to hyperglycemia. Early symptoms are related to hyperglycemia and include polydipsia... read more , end-stage renal disease Chronic Kidney Disease Chronic kidney disease (CKD) is long-standing, progressive deterioration of renal function. Symptoms develop slowly and in advanced stages include anorexia, nausea, vomiting, stomatitis, dysgeusia... read more , and Mönckeberg arteriosclerosis Mönckeberg arteriosclerosis Nonatheromatous arteriosclerosis is age-related fibrosis in the aorta and its major branches. (See also Atherosclerosis.) Arteriosclerosis is a general term for several disorders that cause... read more . A high index may suggest that further vascular studies are needed (toe-brachial index or arterial duplex studies).
Blood pressure and heart rate are measured with the patient supine, seated, and standing; a 1-minute interval is needed between each change in position. A difference in blood pressure of ≤ 10 mm Hg and a change in heart rate of ≤ 20 beats per minute is normal; the difference in blood pressure tends to be a little greater in older patients due to loss of vascular elasticity.
Normally during inspiration, systolic arterial blood pressure can decrease as much as 10 mm Hg, and pulse rate increases to compensate. An exaggeration of this normal response with a greater decrease in systolic blood pressure or weakening of the pulse during inspiration is considered pulsus paradoxus. Pulsus paradoxus occurs in
Constrictive pericarditis Pathophysiology , severe asthma Asthma Asthma is a disease of diffuse airway inflammation caused by a variety of triggering stimuli resulting in partially or completely reversible bronchoconstriction. Symptoms and signs include dyspnea... read more , and occasionally in chronic obstructive pulmonary disease Chronic Obstructive Pulmonary Disease (COPD) Chronic obstructive pulmonary disease (COPD) is airflow limitation caused by an inflammatory response to inhaled toxins, often cigarette smoke. Alpha-1 antitrypsin deficiency and various occupational... read more
Restrictive cardiomyopathy Restrictive Cardiomyopathy Restrictive cardiomyopathy is characterized by noncompliant ventricular walls that resist diastolic filling; one (most commonly the left) or both ventricles may be affected. Symptoms include... read more , severe pulmonary embolism Pulmonary Embolism (PE) Pulmonary embolism (PE) is the occlusion of pulmonary arteries by thrombi that originate elsewhere, typically in the large veins of the legs or pelvis. Risk factors for pulmonary embolism are... read more , and hypovolemic shock (rarely)
Blood pressure decreases during inspiration because negative intrathoracic pressure increases venous return and hence right ventricular (RV) filling; as a result, the interventricular septum bulges slightly into the left ventricular (LV) outflow tract, decreasing cardiac output and thus BP. This mechanism (and the drop in systolic BP) is exaggerated in disorders that cause high negative intrathoracic pressure (eg, asthma) or that restrict RV filling (eg, cardiac tamponade, cardiomyopathy) or outflow (eg, pulmonary embolism).
Pulsus paradoxus is quantified by inflating a BP cuff to just above systolic BP and deflating it very slowly (eg, ≤ 2 mm Hg/heartbeat). The pressure is noted when Korotkoff sounds are first heard (at first, only during expiration) and when Korotkoff sounds are heard continuously. The difference between the pressures is the “amount” of pulsus paradoxus.
Major peripheral pulses in the arms and legs are palpated for symmetry and volume (intensity). Elasticity of the arterial wall is noted. Absence of pulses may suggest an arterial disorder (eg, atherosclerosis Atherosclerosis Atherosclerosis is characterized by patchy intimal plaques (atheromas) that encroach on the lumen of medium-sized and large arteries. The plaques contain lipids, inflammatory cells, smooth muscle... read more ) or systemic embolism. Peripheral pulses may be difficult to feel in obese or muscular people. The pulse has a rapid upstroke, then collapses in disorders with a rapid runoff of arterial blood (eg, arteriovenous communication, aortic regurgitation Aortic Regurgitation Aortic regurgitation (AR) is incompetency of the aortic valve causing backflow from the aorta into the left ventricle during diastole. Causes include valvular degeneration and aortic root dilation... read more ). The pulse is rapid and bounding in hyperthyroidism Hyperthyroidism Hyperthyroidism is characterized by hypermetabolism and elevated serum levels of free thyroid hormones. Symptoms include palpitations, fatigue, weight loss, heat intolerance, anxiety, and tremor... read more and hypermetabolic states; it is slow and sluggish in hypothyroidism Hypothyroidism Hypothyroidism is thyroid hormone deficiency. Symptoms include cold intolerance, fatigue, and weight gain. Signs may include a typical facial appearance, hoarse slow speech, and dry skin. Diagnosis... read more . If pulses are asymmetric, auscultation over peripheral vessels may detect a bruit due to stenosis.
Observation, palpation, and auscultation of both carotid pulses may suggest a specific disorder (see table Carotid Pulse Amplitude and Associated Disorders Carotid Pulse Amplitude and Associated Disorders ). Aging and arteriosclerosis lead to vessel rigidity, which tends to eliminate the characteristic findings. In very young children, the carotid pulse may be normal, even when severe aortic stenosis is present.
Auscultation over the carotid arteries can distinguish murmurs from bruits. Murmurs originate in the heart or great vessels and are usually louder over the upper precordium and diminish toward the neck. Bruits are higher-pitched, are heard only over the arteries, and seem more superficial. An arterial bruit must be distinguished from a venous hum. Unlike an arterial bruit, a venous hum is usually continuous, heard best with the patient sitting or standing, and is eliminated by compression of the ipsilateral internal jugular vein.
The peripheral veins are observed for varicosities Varicose Veins Varicose veins are dilated superficial veins in the lower extremities. Usually, no cause is obvious. Varicose veins are typically asymptomatic but may cause a sense of fullness, pressure, and... read more , arteriovenous malformations (AVMs) and shunts, and overlying inflammation and tenderness due to thrombophlebitis. An AVM or a shunt produces a continuous murmur (heard on auscultation) and often a palpable thrill (because resistance is always lower in the vein than in the artery during systole and diastole).
The neck veins are examined to estimate venous wave height and waveform. Height is proportional to right atrial pressure, and waveform reflects events in the cardiac cycle; both are best observed in the internal jugular vein.
The jugular veins are usually examined with the patient reclining at 45°. The top of the venous column is normally just above the clavicles (upper limit of normal: 4 cm above the sternal notch in a vertical plane). The venous column is elevated in heart failure Heart Failure (HF) Heart failure (HF) is a syndrome of ventricular dysfunction. Left ventricular (LV) failure causes shortness of breath and fatigue, and right ventricular (RV) failure causes peripheral and abdominal... read more , volume overload Volume Overload Volume overload generally refers to expansion of the extracellular fluid (ECF) volume. ECF volume expansion typically occurs in heart failure, kidney failure, nephrotic syndrome, and cirrhosis... read more , cardiac tamponade Cardiac Tamponade Cardiac tamponade is accumulation of blood in the pericardial sac of sufficient volume and pressure to impair cardiac filling. Patients typically have hypotension, muffled heart tones, and distended... read more , constrictive pericarditis Pericarditis Pericarditis is inflammation of the pericardium, often with fluid accumulation in the pericardial space. Pericarditis may be caused by many disorders (eg, infection, myocardial infarction, trauma... read more , tricuspid stenosis Tricuspid Stenosis Tricuspid stenosis (TS) is narrowing of the tricuspid orifice that obstructs blood flow from the right atrium to the right ventricle. Almost all cases result from rheumatic fever. Symptoms include... read more , superior vena cava obstruction, or reduced compliance of the right ventricle. If such conditions are severe, the venous column can extend to jaw level, and its top can be detected only when the patient sits upright or stands. The venous column is low in hypovolemia Volume Depletion Volume depletion, or extracellular fluid (ECF) volume contraction, occurs as a result of loss of total body sodium. Causes include vomiting, excessive sweating, diarrhea, burns, diuretic use... read more .
Normally, the venous column can be briefly elevated by firm hand pressure on the abdomen (hepatojugular or abdominojugular reflux); the column falls back in a few seconds (maximum 3 respiratory cycles or 15 seconds) despite continued abdominal pressure (because a compliant RV increases its stroke volume via the Frank-Starling mechanism). However, the column remains elevated (> 3 cm) during abdominal pressure in disorders that cause a dilated and poorly compliant RV or in obstruction of RV filling by tricuspid stenosis Tricuspid Stenosis Tricuspid stenosis (TS) is narrowing of the tricuspid orifice that obstructs blood flow from the right atrium to the right ventricle. Almost all cases result from rheumatic fever. Symptoms include... read more or right atrial tumor.
Normally, the venous column falls slightly during inspiration as lowered intrathoracic pressure draws blood from the periphery into the vena cava. A rise in the venous column during inspiration (Kussmaul sign) occurs typically in chronic constrictive pericarditis Pericarditis Pericarditis is inflammation of the pericardium, often with fluid accumulation in the pericardial space. Pericarditis may be caused by many disorders (eg, infection, myocardial infarction, trauma... read more , right ventricular myocardial infarction Acute Myocardial Infarction (MI) Acute myocardial infarction is myocardial necrosis resulting from acute obstruction of a coronary artery. Symptoms include chest discomfort with or without dyspnea, nausea, and/or diaphoresis... read more , and chronic obstructive pulmonary disease Chronic Obstructive Pulmonary Disease (COPD) Chronic obstructive pulmonary disease (COPD) is airflow limitation caused by an inflammatory response to inhaled toxins, often cigarette smoke. Alpha-1 antitrypsin deficiency and various occupational... read more (COPD), and can also occur in heart failure and tricuspid stenosis.
Normal jugular vein waves
The a wave is caused by right atrial contraction (systole) and is followed by the x descent, which is caused by atrial relaxation. The c wave, an interruption of the x descent, is caused by the transmitted carotid pulse; it is seldom discerned clinically. The v wave is caused by right atrial filling during ventricular systole (tricuspid valve is closed). The y descent is caused by rapid filling of the right ventricle during ventricular diastole before atrial contraction.
The a waves are increased in pulmonary hypertension and tricuspid valve stenosis. Giant a waves (Cannon waves) occur in atrioventricular dissociation when the atrium contracts while the tricuspid valve is closed. The a waves disappear in atrial fibrillation and are accentuated when RV compliance is poor (eg, in pulmonary hypertension or pulmonic stenosis). The v waves are very prominent in tricuspid regurgitation. The x descent is steep in cardiac tamponade. When RV compliance is poor, the y descent is very abrupt because the elevated column of venous blood rushes into the RV when the tricuspid valve opens, only to be stopped abruptly by the rigid RV wall (in restrictive myopathy) or the pericardium (in constrictive pericarditis).
Chest Inspection and Palpation
Chest contour and any visible cardiac impulses are inspected. The precordium is palpated for pulsations (determining apical impulse and thus cardiac situs) and thrills.
Chest deformities may occur in a number of disorders.
Shield chest and pectus carinatum (a prominent birdlike sternum) may be associated with Marfan syndrome Marfan Syndrome Marfan syndrome consists of connective tissue anomalies resulting in ocular, skeletal, and cardiovascular abnormalities (eg, dilation of ascending aorta, which can lead to aortic dissection)... read more (which may be accompanied by aortic root or mitral valve disease) or Noonan syndrome Primary hypogonadism (which may be accompanied by pulmonic stenosis Pulmonic Stenosis Pulmonic stenosis (PS) is narrowing of the pulmonary outflow tract causing obstruction of blood flow from the right ventricle to the pulmonary artery during systole. Most cases are congenital... read more , atrial septal defects Atrial Septal Defect (ASD) An atrial septal defect (ASD) is an opening in the interatrial septum, causing a left-to-right shunt and volume overload of the right atrium and right ventricle. Children are rarely symptomatic... read more , or hypertrophic cardiomyopathy Hypertrophic Cardiomyopathy Hypertrophic cardiomyopathy is a congenital or acquired disorder characterized by marked ventricular hypertrophy with diastolic dysfunction but without increased afterload (eg, due to valvular... read more ). Rarely, a localized upper chest bulge indicates aortic aneurysm Overview of Aortic Aneurysms Aneurysms are abnormal dilations of arteries caused by weakening of the arterial wall. Common causes include hypertension, atherosclerosis, infection, trauma, and hereditary or acquired connective... read more due to syphilis.
Pectus excavatum (depressed sternum) with a narrow anteroposterior chest diameter and an abnormally straight thoracic spine may be associated with hereditary disorders involving congenital cardiac defects (eg, Turner syndrome Turner Syndrome In Turner syndrome, girls are born with one of their two X chromosomes partly or completely missing. Diagnosis is based on clinical findings and is confirmed by cytogenetic analysis. Treatment... read more , Noonan syndrome Primary hypogonadism ) and sometimes Marfan syndrome Marfan Syndrome Marfan syndrome consists of connective tissue anomalies resulting in ocular, skeletal, and cardiovascular abnormalities (eg, dilation of ascending aorta, which can lead to aortic dissection)... read more .
The patient lays at approximately a 30 to 45 degree angle. Approaching the patient from the right side, the clinician systematically palpates the precordium.
The apical impulse in healthy individuals should be palpable between the 4th and 5th intercostal space just medial to the midclavicular line and cover an area < 2 to 3 cm in diameter.
A central precordial heave is a palpable lifting sensation under the sternum and anterior chest wall to the left of the sternum; it suggests severe right ventricular hypertrophy. Occasionally, in congenital disorders that cause severe RV hypertrophy, the precordium visibly bulges asymmetrically to the left of the sternum.
A sustained thrust at the apex (easily differentiated from the less focal, somewhat diffuse precordial heave of RV hypertrophy) suggests LV hypertrophy.
Abnormal focal systolic impulses in the precordium can sometimes be felt in patients with a dyskinetic ventricular aneurysm. An abnormal diffuse systolic impulse lifts the precordium in patients with severe mitral regurgitation. The lift occurs because the left atrium expands, causing anterior cardiac displacement. A diffuse and inferolaterally displaced apical impulse is found when the LV is dilated and hypertrophied (eg, in mitral regurgitation Mitral Regurgitation Mitral regurgitation (MR) is incompetency of the mitral valve causing flow from the left ventricle (LV) into the left atrium during ventricular systole. MR can be primary (common causes are... read more ).
Thrills are a palpable buzzing sensation present with particularly loud murmurs. Their location suggests the cause (see table Location of Thrills and Associated Disorder Location of Thrills and Associated Disorder ).
A sharp impulse at the 2nd intercostal space to the left of the sternum may result from exaggerated pulmonic valve closure in pulmonary hypertension Pulmonary Hypertension Pulmonary hypertension is increased pressure in the pulmonary circulation. It has many secondary causes; some cases are idiopathic. In pulmonary hypertension, pulmonary vessels may become constricted... read more . A similar early systolic impulse at the cardiac apex may represent closure of a stenotic mitral valve Mitral Stenosis Mitral stenosis is narrowing of the mitral orifice that impedes blood flow from the left atrium to the left ventricle. The usual cause is rheumatic fever. Common complications are pulmonary... read more ; opening of the stenotic valve sometimes can be felt at the beginning of diastole. These findings coincide with an augmented 1st heart sound and an opening snap of mitral stenosis, heard on auscultation.
The lungs are examined for signs of pleural effusion Pleural Effusion Pleural effusions are accumulations of fluid within the pleural space. They have multiple causes and usually are classified as transudates or exudates. Detection is by physical examination and... read more and pulmonary edema Pulmonary Edema Pulmonary edema is acute, severe left ventricular failure with pulmonary venous hypertension and alveolar flooding. Findings are severe dyspnea, diaphoresis, wheezing, and sometimes blood-tinged... read more , which may occur with cardiac disease such as heart failure Heart Failure (HF) Heart failure (HF) is a syndrome of ventricular dysfunction. Left ventricular (LV) failure causes shortness of breath and fatigue, and right ventricular (RV) failure causes peripheral and abdominal... read more . The lung examination Physical Examination Key components in the evaluation of patients with pulmonary symptoms are the history, physical examination, and, in many cases, a chest x-ray. These components establish the need for subsequent... read more includes percussion, palpation, and auscultation.
Percussion is the primary physical maneuver used to detect the presence and level of pleural effusion. Finding areas of dullness during percussion signifies underlying fluid or, less commonly, consolidation.
Palpation includes tactile fremitus (vibration of the chest wall felt while a patient is speaking); fremitus is decreased in pleural effusion and pneumothorax and increased in pulmonary consolidation (eg, lobar pneumonias).
Auscultation of the lungs Auscultation Key components in the evaluation of patients with pulmonary symptoms are the history, physical examination, and, in many cases, a chest x-ray. These components establish the need for subsequent... read more is an important component of the examination of patients with suspected cardiac disease.
The character and volume of breath sounds are useful in differentiating cardiac from pulmonary disorders. Adventitious sounds are abnormal sounds, such as crackles, rhonchi, wheezes, and stridor. Crackles (previously called rales) and wheezes are abnormal lung sounds that may occur in heart failure as well as non-cardiac diseases.
Crackles are discontinuous adventitious breath sounds. Fine crackles are short high-pitched sounds; coarse crackles are longer-lasting low-pitched sounds. Crackles have been compared to the sound of crinkling plastic wrap and can be simulated by rubbing strands of hair together between 2 fingers near one’s ear. They occur most commonly with atelectasis, alveolar filling processes (eg, pulmonary edema in heart failure Heart Failure (HF) Heart failure (HF) is a syndrome of ventricular dysfunction. Left ventricular (LV) failure causes shortness of breath and fatigue, and right ventricular (RV) failure causes peripheral and abdominal... read more ), and interstitial lung disease Overview of Interstitial Lung Disease Interstitial lung diseases are a heterogeneous group of disorders characterized by alveolar septal thickening, fibroblast proliferation, collagen deposition, and, if the process remains unchecked... read more (eg, pulmonary fibrosis); they signify opening of collapsed airways or alveoli.
Wheezes are whistling, musical breath sounds that are worse during expiration than inspiration. Wheezing can be a physical finding or a symptom and is usually associated with dyspnea. Wheezes occur most commonly with asthma but can also occur in cardiac disease such as heart failure Heart Failure (HF) Heart failure (HF) is a syndrome of ventricular dysfunction. Left ventricular (LV) failure causes shortness of breath and fatigue, and right ventricular (RV) failure causes peripheral and abdominal... read more .
Abdominal and Extremity Examination
The abdomen and extremities are examined for signs of fluid overload, which may occur with heart failure as well as noncardiac disorders (eg, renal, hepatic, lymphatic).
In the abdomen, significant fluid overload manifests as ascites Ascites Ascites is free fluid in the peritoneal cavity. The most common cause is portal hypertension. Symptoms usually result from abdominal distention. Diagnosis is based on physical examination and... read more . Marked ascites causes visible abdominal distention, which is tense and nontender to palpation, with shifting dullness on abdominal percussion and a fluid wave. The liver may be distended and slightly tender, with a hepatojugular reflux present.
In the extremities (primarily the legs), fluid overload is manifest as edema Edema Edema is swelling of soft tissues due to increased interstitial fluid. The fluid is predominantly water, but protein and cell-rich fluid can accumulate if there is infection or lymphatic obstruction... read more , which is swelling of soft tissues due to increased interstitial fluid. Edema may be visible on inspection, but modest amounts of edema in very obese or muscular people may be difficult to recognize visually. Thus, extremities are palpated for presence and degree of pitting (visible and palpable depressions caused by pressure from the examiner’s fingers, which displaces the interstitial fluid). The area of edema is examined for extent, symmetry (ie, comparing both extremities), warmth, erythema, and tenderness. With significant fluid overload, edema may also be present over the sacrum, genitals, or both.
Tenderness, erythema, or both, particularly when unilateral, suggests an inflammatory cause (eg, cellulitis or thrombophlebitis). Nonpitting edema is more suggestive of lymphatic or vascular obstruction than fluid overload.
Point-of-Care Ultrasonography (POCUS)
(See also Echocardiography Echocardiography This photo shows a patient having echocardiography. This image shows all 4 cardiac chambers and the tricupsid and mitral valves. Echocardiography uses ultrasound waves to produce an image of... read more .)
Point-of-care ultrasonography (POCUS) is a complement to the physical examination that uses small, inexpensive, battery-operated ultrasound devices operated by the clinician at the bedside. Both 2-dimensional and color Doppler techniques can be used. It has been shown that a brief, focused ultrasound examination can improve detection of various cardiac anomalies and confirm findings from physical examination or sometimes make a diagnosis in the absence of physical findings. Common uses include identification of (1, 2 Point of care ultrasound references Complete examination of all systems is essential to detect peripheral and systemic effects of cardiac disorders and evidence of noncardiac disorders that might affect the heart. Examination... read more )
Left ventricular systolic dysfunction (with global or regional wall motion abnormality)
Left ventricular regional wall motion abnormality (with reduced or normal systolic function)
Elevated left heart filling pressures (enlarged left atrium)
Valve structure and function
Pulmonary edema (vertical B-lines in the lung fields)
Systemic venous congestion (dilated inferior vena cava)
Pericardial effusion and cardiac tamponade
Adequate training in doing brief ultrasound examinations is essential to ensure high image quality and accurate interpretation (2 Point of care ultrasound references Complete examination of all systems is essential to detect peripheral and systemic effects of cardiac disorders and evidence of noncardiac disorders that might affect the heart. Examination... read more ). Importantly, POCUS should be used to augment rather than replace the physical examination.
Point of care ultrasound references
1. Kimura BJ: Point-of-care cardiac ultrasound techniques in the physical examination: better at the bedside. Heart 103:987–994, 2017. doi: 10.1136/heartjnl-2016-309915
2. Spencer KT, Kimura BJ, Korcarz CE, et al: Focused Cardiac Ultrasound: Recommendations from the American Society of Echocardiography. J Am Soc Echocardiogr 26:567–581, 2013. doi: 10.1016/j.echo.2013.04.001